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Organoids
Z Zhao, X Chen, AM Dowbaj, A Sljukic… - Nature Reviews …, 2022 - nature.com
Organoids are simple tissue-engineered cell-based in vitro models that recapitulate many
aspects of the complex structure and function of the corresponding in vivo tissue. They can …
aspects of the complex structure and function of the corresponding in vivo tissue. They can …
Artificial intelligence in cancer target identification and drug discovery
Artificial intelligence is an advanced method to identify novel anticancer targets and discover
novel drugs from biology networks because the networks can effectively preserve and …
novel drugs from biology networks because the networks can effectively preserve and …
SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity
Cancer cells evade T cell-mediated killing through tumour–immune interactions whose
mechanisms are not well understood,. Dendritic cells (DCs), especially type-1 conventional …
mechanisms are not well understood,. Dendritic cells (DCs), especially type-1 conventional …
CXCR6 orchestrates brain CD8+ T cell residency and limits mouse Alzheimer's disease pathology
Neurodegenerative diseases, including Alzheimer's disease (AD), are characterized by
innate immune-mediated inflammation, but functional and mechanistic effects of the …
innate immune-mediated inflammation, but functional and mechanistic effects of the …
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues
Although cellular senescence drives multiple age-related co-morbidities through the
senescence-associated secretory phenotype, in vivo senescent cell identification remains …
senescence-associated secretory phenotype, in vivo senescent cell identification remains …
Enrichr-KG: bridging enrichment analysis across multiple libraries
Gene and protein set enrichment analysis is a critical step in the analysis of data collected
from omics experiments. Enrichr is a popular gene set enrichment analysis web-server …
from omics experiments. Enrichr is a popular gene set enrichment analysis web-server …
Convergent selection of a WD40 protein that enhances grain yield in maize and rice
W Chen, L Chen, X Zhang, N Yang, J Guo, M Wang… - Science, 2022 - science.org
A better understanding of the extent of convergent selection among crops could greatly
improve breeding programs. We found that the quantitative trait locus KRN2 in maize and its …
improve breeding programs. We found that the quantitative trait locus KRN2 in maize and its …
A clinically applicable integrative molecular classification of meningiomas
Meningiomas are the most common primary intracranial tumour in adults. Patients with
symptoms are generally treated with surgery as there are no effective medical therapies. The …
symptoms are generally treated with surgery as there are no effective medical therapies. The …
Neuromaps: structural and functional interpretation of brain maps
Imaging technologies are increasingly used to generate high-resolution reference maps of
brain structure and function. Comparing experimentally generated maps to these reference …
brain structure and function. Comparing experimentally generated maps to these reference …
Persistent serum protein signatures define an inflammatory subcategory of long COVID
Long COVID or post-acute sequelae of SARS-CoV-2 (PASC) is a clinical syndrome featuring
diverse symptoms that can persist for months following acute SARS-CoV-2 infection. The …
diverse symptoms that can persist for months following acute SARS-CoV-2 infection. The …