CRISPR-based diagnostics

MM Kaminski, OO Abudayyeh, JS Gootenberg… - Nature Biomedical …, 2021 - nature.com
The accurate and timely diagnosis of disease is a prerequisite for efficient therapeutic
intervention and epidemiological surveillance. Diagnostics based on the detection of nucleic …

Antimicrobial activity of Eucalyptus camaldulensis Dehn. plant extracts and essential oils: A review

VA Sabo, P Knezevic - Industrial crops and products, 2019 - Elsevier
Eucalyptus has become one of the world's most widely planted genera and E.
camaldulensis (The River Red Gum) is a plantation species in many parts of the world. The …

Genome-wide map** of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements

I Manfredonia, C Nithin… - Nucleic acids …, 2020 - academic.oup.com
SARS-CoV-2 is a betacoronavirus with a linear single-stranded, positive-sense RNA
genome, whose outbreak caused the ongoing COVID-19 pandemic. The ability of …

Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents

EL Blanchard, D Vanover, SS Bawage, PM Tiwari… - Nature …, 2021 - nature.com
Cas13a has been used to target RNA viruses in cell culture, but efficacy has not been
demonstrated in animal models. In this study, we used messenger RNA (mRNA)-encoded …

Antiviral drugs in aquatic environment and wastewater treatment plants: a review on occurrence, fate, removal and ecotoxicity

C Nannou, A Ofrydopoulou, E Evgenidou… - Science of the Total …, 2020 - Elsevier
The environmental release of antiviral drugs is of considerable concern due to potential
ecosystem alterations and the development of antiviral resistance. As a result, interest on …

Antiviral activity of plants and their isolated bioactive compounds: An update

M Denaro, A Smeriglio, D Barreca… - Phytotherapy …, 2020 - Wiley Online Library
Viral infections represent one of the main causes of disease worldwide, especially today due
to the increase of migration, global travel, and urbanization. The several side effects of the …

Recommendations for improving statistical inference in population genomics

P Johri, CF Aquadro, M Beaumont, B Charlesworth… - PLoS …, 2022 - journals.plos.org
The field of population genomics has grown rapidly in response to the recent advent of
affordable, large-scale sequencing technologies. As opposed to the situation during the …

Trends and targets in antiviral phototherapy

A Wiehe, JM O'Brien, MO Senge - Photochemical & Photobiological …, 2019 - pubs.rsc.org
Photodynamic therapy (PDT) is a well-established treatment option in the treatment of
certain cancerous and pre-cancerous lesions. Though best-known for its application in …

Host-directed antiviral therapy

N Kumar, S Sharma, R Kumar, BN Tripathi… - Clinical microbiology …, 2020 - Am Soc Microbiol
Antiviral drugs have traditionally been developed by directly targeting essential viral
components. However, this strategy often fails due to the rapid generation of drug-resistant …

Phytochemicals as antiviral agents: recent updates

R Ghildiyal, V Prakash, VK Chaudhary, V Gupta… - Plant-derived bioactives …, 2020 - Springer
The epidemic of viral diseases is a global concern, mandating an urgent need of most
promising antivirals. Some of the viral diseases can be cured by approved antiviral drugs …