microRNAs and their roles in plant development

Q Dong, B Hu, C Zhang - Frontiers in plant science, 2022 - frontiersin.org
Small RNAs are short non-coding RNAs with a length ranging between 20 and 24
nucleotides. Of these, microRNAs (miRNAs) play a distinct role in plant development …

Identifying miRNAs, targets and functions

B Liu, J Li, MJ Cairns - Briefings in bioinformatics, 2014 - academic.oup.com
Abstract microRNAs (miRNAs) are small endogenous non-coding RNAs that function as the
universal specificity factors in post-transcriptional gene silencing. Discovering miRNAs …

A fast PC algorithm for high dimensional causal discovery with multi-core PCs

TD Le, T Hoang, J Li, L Liu, H Liu… - IEEE/ACM transactions …, 2016 - ieeexplore.ieee.org
Discovering causal relationships from observational data is a crucial problem and it has
applications in many research areas. The PC algorithm is the state-of-the-art constraint …

miRModuleNet: detecting miRNA-mRNA regulatory modules

M Yousef, G Goy, B Bakir-Gungor - Frontiers in Genetics, 2022 - frontiersin.org
Increasing evidence that microRNAs (miRNAs) play a key role in carcinogenesis has
revealed the need for elucidating the mechanisms of miRNA regulation and the roles of …

Identifying functional miRNA–mRNA regulatory modules with correspondence latent dirichlet allocation

B Liu, L Liu, A Tsykin, GJ Goodall, JE Green… - …, 2010 - academic.oup.com
Motivation: MicroRNAs (miRNAs) are small non-coding RNAs that cause mRNA degradation
and translational inhibition. They are important regulators of development and cellular …

Network modeling of microRNA–mRNA interactions in neuroblastoma tumorigenesis identifies miR-204 as a direct inhibitor of MYCN

CY Ooi, DR Carter, B Liu, C Mayoh, A Beckers… - Cancer …, 2018 - aacrjournals.org
Neuroblastoma is a pediatric cancer of the sympathetic nervous system where MYCN
amplification is a key indicator of poor prognosis. However, mechanisms by which MYCN …

miRNAs in NK cell-based immune responses and cancer immunotherapy

S Pesce, M Greppi, E Ferretti, V Obino… - Frontiers in Cell and …, 2020 - frontiersin.org
The incidence of certain forms of tumors has increased progressively in recent years and is
expected to continue growing as life expectancy continues to increase. Tumor-infiltrating NK …

Understanding principles of miRNA target recognition and function through integrated biological and bioinformatics approaches

AP Carroll, GJ Goodall, B Liu - Wiley Interdisciplinary Reviews …, 2014 - Wiley Online Library
In recent times, microRNA (miRNA) have emerged as primary regulators of fundamental
biological processes including cellular differentiation, proliferation, apoptosis, as well as …

A review on methods for predicting miRNA–mRNA regulatory modules

M Madhumita, S Paul - Journal of Integrative Bioinformatics, 2022 - degruyter.com
Identification of complex interactions between miRNAs and mRNAs in a regulatory network
helps better understand the underlying biological processes. Previously, identification of …

[HTML][HTML] MicroRNA-regulated protein-protein interaction networks and their functions in breast cancer

CH Lee, WH Kuo, CC Lin, YJ Oyang… - International journal of …, 2013 - mdpi.com
MicroRNAs, which are small endogenous RNA regulators, have been associated with
various types of cancer. Breast cancer is a major health threat for women worldwide. Many …