Red nucleus structure and function: from anatomy to clinical neurosciences

GA Basile, M Quartu, S Bertino, MP Serra, M Boi… - Brain Structure and …, 2021 - Springer
The red nucleus (RN) is a large subcortical structure located in the ventral midbrain.
Although it originated as a primitive relay between the cerebellum and the spinal cord …

[HTML][HTML] The many facets of motor learning and their relevance for Parkinson's disease

L Marinelli, A Quartarone, M Hallett, G Frazzitta… - Clinical …, 2017 - Elsevier
The final goal of motor learning, a complex process that includes both implicit and explicit (or
declarative) components, is the optimization and automatization of motor skills. Motor …

In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain–striatum–cortex assembloids

D Reumann, C Krauditsch, M Novatchkova, E Sozzi… - Nature …, 2023 - nature.com
Ventral midbrain dopaminergic neurons project to the striatum as well as the cortex and are
involved in movement control and reward-related cognition. In Parkinson's disease …

The cortico-basal ganglia-cerebellar network: past, present and future perspectives

D Milardi, A Quartarone, A Bramanti… - Frontiers in systems …, 2019 - frontiersin.org
Much of our present understanding of the function and operation of the basal ganglia rests
on models of anatomical connectivity derived from tract-tracing approaches in rodents and …

Basal ganglia for beginners: the basic concepts you need to know and their role in movement control

GS Rocha, MAM Freire, AM Britto, KM Paiva… - Frontiers in Systems …, 2023 - frontiersin.org
The basal ganglia are a subcortical collection of interacting clusters of cell bodies, and are
involved in reward, emotional, and motor circuits. Within all the brain processing necessary …

[HTML][HTML] Functional connectome of arousal and motor brainstem nuclei in living humans by 7 Tesla resting-state fMRI

K Singh, S Cauzzo, MG García-Gomar, M Stauder… - NeuroImage, 2022 - Elsevier
Brainstem nuclei play a pivotal role in many functions, such as arousal and motor control.
Nevertheless, the connectivity of arousal and motor brainstem nuclei is understudied in …

The cerebellar dopaminergic system

P Flace, P Livrea, GA Basile, D Galletta… - Frontiers in systems …, 2021 - frontiersin.org
In the central nervous system (CNS), dopamine (DA) is involved in motor and cognitive
functions. Although the cerebellum is not been considered an elective dopaminergic region …

New insights into cortico-basal-cerebellar connectome: clinical and physiological considerations

A Quartarone, A Cacciola, D Milardi, MF Ghilardi… - Brain, 2020 - academic.oup.com
The current model of the basal ganglia system based on the 'direct','indirect'and
'hyperdirect'pathways provides striking predictions about basal ganglia function that have …

A connectomic analysis of the human basal ganglia network

A Cacciola, A Calamuneri, D Milardi… - Frontiers in …, 2017 - frontiersin.org
The current model of basal ganglia circuits has been introduced almost two decades ago
and has settled the basis for our understanding of basal ganglia physiology and movement …

The cortico-rubral and cerebello-rubral pathways are topographically organized within the human red nucleus

A Cacciola, D Milardi, GA Basile, S Bertino… - Scientific reports, 2019 - nature.com
Abstract The Red Nucleus (RN) is a large nucleus located in the ventral midbrain: it is
subdivided into a small caudal magnocellular part (mRN) and a large rostral parvocellular …