Assembly of cell regulatory systems through protein interaction domains

T Pawson, P Nash - science, 2003 - science.org
The sequencing of complete genomes provides a list that includes the proteins responsible
for cellular regulation. However, this does not immediately reveal what these proteins do …

A view to a kill: the bacterial type VI secretion system

BT Ho, TG Dong, JJ Mekalanos - Cell host & microbe, 2014 - cell.com
The bacterial type VI secretion system (T6SS) is an organelle that is structurally and
mechanistically analogous to an intracellular membrane-attached contractile phage tail …

Type VI secretion: a beginner's guide

LEH Bingle, CM Bailey, MJ Pallen - Current opinion in microbiology, 2008 - Elsevier
Type VI secretion is a newly described mechanism for protein transport across the cell
envelope of Gram-negative bacteria. Components that have been partially characterised …

Type three secretion system in attaching and effacing pathogens

MO Gaytán, VI Martínez-Santos, E Soto… - Frontiers in cellular …, 2016 - frontiersin.org
Enteropathogenic Escherichia coli and enterohemorrhagic E. coli are diarrheagenic
bacterial human pathogens that cause severe gastroenteritis. These enteric pathotypes …

The bacterial type VI secretion machine: yet another player for protein transport across membranes

A Filloux, A Hachani, S Bleves - Microbiology, 2008 - microbiologyresearch.org
Several secretion systems have evolved that are widespread among Gram-negative
bacteria. Recently, a new secretion system was recognized, which is named the type VI …

Threonine phosphorylation post-translationally regulates protein secretion in Pseudomonas aeruginosa

JD Mougous, CA Gifford, TL Ramsdell… - Nature cell …, 2007 - nature.com
Secreted proteins are crucial to the arsenal of bacterial pathogens. Although optimal activity
of these proteins is likely to require precise regulation of release, the signalling events that …

Assembly of the bacterial type III secretion machinery

A Diepold, S Wagner - FEMS microbiology reviews, 2014 - academic.oup.com
Many bacteria that live in contact with eukaryotic hosts, whether as symbionts or as
pathogens, have evolved mechanisms that manipulate host cell behaviour to their benefit …

Infection-Blocking Genes of a Symbiotic Rhizobium leguminosarum Strain That Are Involved in Temperature-Dependent Protein Secretion

MR Bladergroen, K Badelt… - Molecular plant-microbe …, 2003 - Am Phytopath Society
Rhizobium leguminosarum strain RBL5523 is able to form nodules on pea, but these
nodules are ineffective for nitrogen fixation. The impairment in nitrogen fixation appears to …

Corynebacterial protein kinase G controls 2-oxoglutarate dehydrogenase activity via the phosphorylation status of the OdhI protein

A Niebisch, A Kabus, C Schultz, B Weil… - Journal of Biological …, 2006 - ASBMB
A novel regulatory mechanism for control of the ubiquitous 2-oxoglutarate dehydrogenase
complex (ODH), a key enzyme of the tricarboxylic acid cycle, was discovered in the …

A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria

CL Gee, KG Papavinasasundaram, SR Blair… - Science …, 2012 - science.org
Prokaryotic cell wall biosynthesis is coordinated with cell growth and division, but the
mechanisms regulating this dynamic process remain obscure. Here, we describe a …