Targeting phenotypic heterogeneity in benign prostatic hyperplasia
Benign prostatic hyperplasia and associated lower urinary tract symptoms remain difficult to
treat medically, resulting in hundreds of thousands of surgeries performed annually in …
treat medically, resulting in hundreds of thousands of surgeries performed annually in …
In Vivo Experiments with Dental Pulp Stem Cells for Pulp‐Dentin Complex Regeneration
In recent years, many studies have examined the pulp‐dentin complex regeneration with
DPSCs. While it is important to perform research on cells, scaffolds, and growth factors, it is …
DPSCs. While it is important to perform research on cells, scaffolds, and growth factors, it is …
RNA-binding protein DDX3 mediates posttranscriptional regulation of androgen receptor: a mechanism of castration resistance
JE Vellky, ST McSweeney… - Proceedings of the …, 2020 - National Acad Sciences
Prostate cancer (CaP) driven by androgen receptor (AR) is treated with androgen
deprivation; however, therapy failure results in lethal castration-resistant prostate cancer …
deprivation; however, therapy failure results in lethal castration-resistant prostate cancer …
Estrogen receptor-α is a key mediator and therapeutic target for bladder complications of benign prostatic hyperplasia
Purpose Estrogens are important in prostate growth and have a role in benign prostatic
hyperplasia. However, to our knowledge no current therapy directly targets estrogen action …
hyperplasia. However, to our knowledge no current therapy directly targets estrogen action …
GH action in prostate cancer cells promotes proliferation, limits apoptosis, and regulates cancer-related gene expression
CJ Unterberger, VI Maklakova, M Lazar… - …, 2022 - academic.oup.com
Previous studies investigating the effects of blocking the growth hormone (GH)/insulin-like
growth factor-1 (IGF-1) axis in prostate cancer found no effects of the growth hormone …
growth factor-1 (IGF-1) axis in prostate cancer found no effects of the growth hormone …
Replication Study: The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
X Yan, B Tang, B Chen, Y Shan, H Yang - Elife, 2019 - elifesciences.org
As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Li
et al., 2015), that described how we intended to replicate selected experiments from the …
et al., 2015), that described how we intended to replicate selected experiments from the …
Mutational landscapes of sequential prostate metastases and matched patient derived xenografts during enzalutamide therapy
Development of iPSC-derived human bone marrow organoid for autonomous hematopoiesis and patient-derived HSPC engraftment
Current efforts in translational studies in hematology often rely on immunodeficient mouse
models for engrafting patient-derived hematopoietic stem and progenitor cells (HSPCs), yet …
models for engrafting patient-derived hematopoietic stem and progenitor cells (HSPCs), yet …
Prostate cancer xenografts and hormone induced prostate carcinogenesis
Despite the advancement of transgenic and gene knockout animal models in the prostate
cancer research, there is still a need for utilizing xenograft models. Xenografts can be grown …
cancer research, there is still a need for utilizing xenograft models. Xenografts can be grown …
The mTOR Inhibitor Rapamycin Counteracts Follicle Activation Induced by Ovarian Cryopreservation in Murine Transplantation Models
Background and Objectives: Ovarian tissue cryopreservation followed by
autotransplantation (OTCTP) is currently the only fertility preservation option for prepubertal …
autotransplantation (OTCTP) is currently the only fertility preservation option for prepubertal …