Surveys and registries are needed to verify that real-life daily practice is in kee** with what
is recommended in the guidelines, thus completing the loop between clinical research …

Methods Patients with AAAs are defined as male or female patients with asymptomatic,
symptomatic or ruptured AAA with fusiform dilatation. This document does not cover patients …

Background Most meta-analyses in systematic reviews, including Cochrane ones, do not
have sufficient statistical power to detect or refute even large intervention effects. This is why …

In the GRADE approach, the strength of a recommendation reflects the extent to which we
can be confident that the composite desirable effects of a management strategy outweigh …

GRADE suggests that examination of 95% confidence intervals (CIs) provides the optimal
primary approach to decisions regarding imprecision. For practice guidelines, rating down …

Background There is increasing awareness that meta-analyses require a sufficiently large
information size to detect or reject an anticipated intervention effect. The required …

A joint initiative by the British Thoracic Society and the Society for Cardiothoracic Surgery in
Great Britain and Ireland was undertaken to update the 2001 guidelines for the selection …

Thus, the task of writing Guidelines or Expert Consensus Documents covers not only the
integration of the most recent research, but also the creation of educational tools and …

Arterial blood pressure is the driving force for organ perfusion. Although hypotension is
common in acute care, there is a lack of accepted criteria for its definition. Most practitioners …

Background Infection after surgery and trauma is a major cause of increased morbidity,
mortality, and cost. Alterations of the hosts immune system following these insults is believed …