At different stages of any research project, molecular biologists need to choose—often
somewhat arbitrarily, even after careful statistical data analysis—which genes or proteins to …

The reference human genome sequence set the stage for studies of genetic variation and its
association with human disease, but epigenomic studies lack a similar reference. To …

Increasing quantitative data generated from transcriptomics and proteomics require
integrative strategies for analysis. Here, we present an R package, clusterProfiler that …

Regulated transcription controls the diversity, developmental pathways and spatial
organization of the hundreds of cell types that make up a mammal. Using single-molecule …

Abstract The Biological General Repository for Interaction Datasets (BioGRID:
http://thebiogrid. org) is an open access database that houses genetic and protein …

Disease ontology (DO) annotates human genes in the context of disease. DO is important
annotation in translating molecular findings from high-throughput data to clinical relevance …

Abstract The Disease Ontology (DO) database (http://disease-ontology. org) represents a
comprehensive knowledge base of 8043 inherited, developmental and acquired human …

Motivation A large number of protein sequences are becoming available through the
application of novel high-throughput sequencing technologies. Experimental functional …