Current approaches to the management of brain metastases

JH Suh, R Kotecha, ST Chao, MS Ahluwalia… - Nature reviews Clinical …, 2020 - nature.com
Brain metastases are a very common manifestation of cancer that have historically been
approached as a single disease entity given the uniform association with poor clinical …

Single-and multifraction stereotactic radiosurgery dose/volume tolerances of the brain

MT Milano, J Grimm, A Niemierko, SG Soltys… - International Journal of …, 2021 - Elsevier
Purpose As part of the American Association of Physicists in Medicine Working Group on
Stereotactic Body Radiotherapy investigating normal tissue complication probability (NTCP) …

Standardization of brain MR images across machines and protocols: bridging the gap for MRI-based radiomics

A Carré, G Klausner, M Edjlali, M Lerousseau… - Scientific reports, 2020 - nature.com
Radiomics relies on the extraction of a wide variety of quantitative image-based features to
provide decision support. Magnetic resonance imaging (MRI) contributes to the …

Artificial intelligence assists precision medicine in cancer treatment

J Liao, X Li, Y Gan, S Han, P Rong, W Wang… - Frontiers in …, 2023 - frontiersin.org
Cancer is a major medical problem worldwide. Due to its high heterogeneity, the use of the
same drugs or surgical methods in patients with the same tumor may have different curative …

Consensus recommendations for a standardized brain tumor imaging protocol for clinical trials in brain metastases

TJ Kaufmann, M Smits, J Boxerman, R Huang… - Neuro …, 2020 - academic.oup.com
A recent meeting was held on March 22, 2019, among the FDA, clinical scientists,
pharmaceutical and biotech companies, clinical trials cooperative groups, and patient …

Radiomics in neuro-oncology: Basics, workflow, and applications

P Lohmann, N Galldiks, M Kocher, A Heinzel, CP Filss… - Methods, 2021 - Elsevier
Over the last years, the amount, variety, and complexity of neuroimaging data acquired in
patients with brain tumors for routine clinical purposes and the resulting number of imaging …

Radiomics in neuro-oncological clinical trials

P Lohmann, E Franceschi, P Vollmuth… - The Lancet Digital …, 2022 - thelancet.com
The development of clinical trials has led to substantial improvements in the prevention and
treatment of many diseases, including brain cancer. Advances in medicine, such as …

Imaging challenges of immunotherapy and targeted therapy in patients with brain metastases: response, progression, and pseudoprogression

N Galldiks, M Kocher, G Ceccon, JM Werner… - Neuro …, 2020 - academic.oup.com
The advent of immunotherapy using immune checkpoint inhibitors (ICIs) and targeted
therapy (TT) has dramatically improved the prognosis of various cancer types. However …

Applications of radiomics and machine learning for radiotherapy of malignant brain tumors

M Kocher, MI Ruge, N Galldiks, P Lohmann - Strahlentherapie und …, 2020 - Springer
Background Magnetic resonance imaging (MRI) and amino acid positron-emission
tomography (PET) of the brain contain a vast amount of structural and functional information …

FET PET radiomics for differentiating pseudoprogression from early tumor progression in glioma patients post-chemoradiation

P Lohmann, MA Elahmadawy, R Gutsche, JM Werner… - Cancers, 2020 - mdpi.com
Simple Summary Following chemoradiation with alkylating agents in glioma patients,
structural magnetic resonance imaging (MRI) may suggest tumor progression which …