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RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?
Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …
An emphasis on the interaction of signaling pathways highlights the role of miRNAs in the etiology and treatment resistance of gastric cancer
Gastric cancer (GC) is 4th in incidence and mortality rates globally. Several genetic and
epigenetic factors, including microRNAs (miRNAs), affect its initiation and progression …
epigenetic factors, including microRNAs (miRNAs), affect its initiation and progression …
A review of the biological role of miRNAs in prostate cancer suppression and progression
Prostate cancer (PC) is the third-leading cause of cancer-related deaths worldwide.
Although the current treatment strategies are progressing rapidly, PC is still representing a …
Although the current treatment strategies are progressing rapidly, PC is still representing a …
High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer
Targeting exosome biogenesis and release may have potential clinical implications for
cancer therapy. Herein, we have optimized a quantitative high throughput screen (qHTS) …
cancer therapy. Herein, we have optimized a quantitative high throughput screen (qHTS) …
Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate …
Emerging evidence links exosomes to cancer progression by the trafficking of oncogenic
factors and neoplastic reprogramming of stem cells. This necessitates identification and …
factors and neoplastic reprogramming of stem cells. This necessitates identification and …
Exosomes: diagnostic biomarkers and therapeutic delivery vehicles for cancer
Exosomes are described as nanoscale extracellular vesicles (EVs) secreted by multiple cell
types and extensively distributed in various biological fluids. They contain multifarious …
types and extensively distributed in various biological fluids. They contain multifarious …
Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting
While there are myriad mechanisms of primary and acquired resistance to conventional and
next-generation hormonal therapies in prostate cancer, the potential role of androgen …
next-generation hormonal therapies in prostate cancer, the potential role of androgen …
Clinical relevance of androgen receptor alterations in prostate cancer
Prostate cancer (PC) remains a leading cause of cancer-related deaths among men
worldwide, despite continuously improved treatment strategies. Patients with metastatic …
worldwide, despite continuously improved treatment strategies. Patients with metastatic …
Role of noncoding RNA in drug resistance of prostate cancer
L Ding, R Wang, D Shen, S Cheng, H Wang, Z Lu… - Cell death & …, 2021 - nature.com
Prostate cancer is one of the most prevalent forms of cancer around the world. Androgen-
deprivation treatment and chemotherapy are the curative approaches used to suppress …
deprivation treatment and chemotherapy are the curative approaches used to suppress …
The HNRNPF/H RNA binding proteins and disease
T Brownmiller, NJ Caplen - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
The members of the HNRNPF/H family of heterogeneous nuclear RNA proteins—HNRNPF,
HNRNPH1, HNRNPH2, HNRNPH3, and GRSF1, are critical regulators of RNA maturation …
HNRNPH1, HNRNPH2, HNRNPH3, and GRSF1, are critical regulators of RNA maturation …