Tissue engineering: Current status and future perspectives
PK Chandra, S Soker, A Atala - Principles of tissue engineering, 2020 - Elsevier
The field of tissue engineering (TE) has made tremendous progress in the past decade and
is still evolving. It is not only now possible to control cells and their environments more …
is still evolving. It is not only now possible to control cells and their environments more …
Human pluripotent stem cell‐derived products: advances towards robust, scalable and cost‐effective manufacturing strategies
MJ Jenkins, SS Farid - Biotechnology journal, 2015 - Wiley Online Library
The ability to develop cost‐effective, scalable and robust bioprocesses for human pluripotent
stem cells (hPSCs) will be key to their commercial success as cell therapies and tools for …
stem cells (hPSCs) will be key to their commercial success as cell therapies and tools for …
A scalable system for production of functional pancreatic progenitors from human embryonic stem cells
TC Schulz, HY Young, AD Agulnick, MJ Babin… - PloS one, 2012 - journals.plos.org
Development of a human embryonic stem cell (hESC)-based therapy for type 1 diabetes will
require the translation of proof-of-principle concepts into a scalable, controlled, and …
require the translation of proof-of-principle concepts into a scalable, controlled, and …
Generation of functional hepatocyte-like cells from human pluripotent stem cells in a scalable suspension culture
Recent advances in human embryonic and induced pluripotent stem cell-based therapies in
animal models of hepatic failure have led to an increased appreciation of the need to …
animal models of hepatic failure have led to an increased appreciation of the need to …
[HTML][HTML] The microwell-mesh: A novel device and protocol for the high throughput manufacturing of cartilage microtissues
Microwell platforms are frequently described for the efficient and uniform manufacture of 3-
dimensional (3D) multicellular microtissues. Multiple partial or complete medium exchanges …
dimensional (3D) multicellular microtissues. Multiple partial or complete medium exchanges …
Engineering three-dimensional stem cell morphogenesis for the development of tissue models and scalable regenerative therapeutics
The physiochemical stem cell microenvironment regulates the delicate balance between self-
renewal and differentiation. The three-dimensional assembly of stem cells facilitates cellular …
renewal and differentiation. The three-dimensional assembly of stem cells facilitates cellular …
Generation of beta cells from human pluripotent stem cells: potential for regenerative medicine
MC Nostro, G Keller - Seminars in cell & developmental biology, 2012 - Elsevier
The loss of beta cells in Type I diabetes ultimately leads to insulin dependence and major
complications that are difficult to manage by insulin injections. Given the complications …
complications that are difficult to manage by insulin injections. Given the complications …
Analysis of the effects of bench-scale cell culture platforms and inoculum cell concentrations on PSC aggregate formation and culture
DG Iworima, RK Baker, JM Piret… - Frontiers in Bioengineering …, 2023 - frontiersin.org
Introduction: Human pluripotent stem cells (hPSCs) provide many opportunities for
application in regenerative medicine due to their ability to differentiate into cells from all …
application in regenerative medicine due to their ability to differentiate into cells from all …
Technological progress and challenges towards cGMP manufacturing of human pluripotent stem cells based therapeutic products for allogeneic and autologous cell …
Recent technological advances in the generation, characterization, and bioprocessing of
human pluripotent stem cells (hPSCs) have created new hope for their use as a source for …
human pluripotent stem cells (hPSCs) have created new hope for their use as a source for …
The physics of organoids: a biophysical approach to understanding organogenesis
S Dahl-Jensen, A Grapin-Botton - Development, 2017 - journals.biologists.com
Organoids representing a diversity of tissues have recently been created, bridging the gap
between cell culture and experiments performed in vivo. Being small and amenable to …
between cell culture and experiments performed in vivo. Being small and amenable to …