[HTML][HTML] Current trends in the pharmacological management of Chagas disease

V Ribeiro, N Dias, T Paiva, L Hagström-Bex… - International Journal for …, 2020 - Elsevier
Chagas disease (CD) is a tropical neglected illness, affecting mainly populations of low
socioeconomic status in Latin America. An estimated 6 to 8 million people worldwide are …

Review on Experimental Treatment Strategies Against Trypanosoma cruzi

AL Mazzeti, P Capelari-Oliveira, MT Bahia… - Journal of …, 2021 - Taylor & Francis
Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Currently, only nitroheterocyclic nifurtimox (NFX) and benznidazole (BNZ) are …

Therapeutical approaches under investigation for treatment of Chagas disease

MT Bahia, LF Diniz, VCF Mosqueira - Expert opinion on …, 2014 - Taylor & Francis
Introduction: A century after its discovery, American trypanosomiasis or Chagas disease
remains a serious health problem in Latin America, where it affects around 7–8 million …

Nanomedicines against Chagas disease: an update on therapeutics, prophylaxis and diagnosis

MJ Morilla, EL Romero - Nanomedicine, 2015 - Taylor & Francis
Chagas disease is a neglected parasitic infection caused by the protozoan Trypanosoma
cruzi. After a mostly clinically silent acute phase, the disease becomes a lifelong chronic …

PEGylated and functionalized polylactide-based nanocapsules: An overview

MA de Oliveira, RS Araújo, VCF Mosqueira - International Journal of …, 2023 - Elsevier
Polymeric nanocapsules (NC) are versatile mixed vesicular nanocarriers, generally
containing a lipid core with a polymeric wall. They have been first developed over four …

From Benznidazole to new drugs: Nanotechnology contribution in Chagas disease

DC Gomes, TS Medeiros, EL Alves Pereira… - International Journal of …, 2023 - mdpi.com
Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Benznidazole and nifurtimox are the two approved drugs for their treatment, but both …

[HTML][HTML] Efficacy of nanoemulsion with Pterodon emarginatus Vogel oleoresin for topical treatment of cutaneous leishmaniasis

MYM Kawakami, LO Zamora, RS Araújo… - Biomedicine & …, 2021 - Elsevier
Cutaneous leishmaniasis (CL) is a neglected tropical skin disease caused by the protozoan
genus Leishmania. The treatment is restricted to a handful number of drugs that exhibit toxic …

Nanoparticulate drug delivery systems for the treatment of neglected tropical protozoan diseases

G Volpedo, L Costa, N Ryan, G Halsey… - Journal of Venomous …, 2019 - SciELO Brasil
Abstract Neglected Tropical Diseases (NTDs) comprise of a group of seventeen infectious
conditions endemic in many develo** countries. Among these diseases are three of …

[HTML][HTML] Treatments and the perspectives of develo** a vaccine for Chagas disease

PSG Farani, KM Jones, C Poveda - Vaccines, 2024 - mdpi.com
Chagas disease (CD) treatment and vaccine development are critical due to the significant
health burden caused by the disease, especially in Latin America. Current treatments …

Advances in nanocarriers as drug delivery systems in Chagas disease

C Quijia Quezada, CS Azevedo… - International journal …, 2019 - Taylor & Francis
Chagas disease is one of the most important public health problems in Latin America due to
its high mortality and morbidity levels. There is no effective treatment for this disease since …