What is known about breast cancer in young women?

JW Zhu, P Charkhchi, S Adekunte, MR Akbari - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is the most common cancer affecting women under 40 years
of age worldwide, with an increasing number of cases diagnosed each year. Despite this …

Molecular subtypes and local-regional control of breast cancer

SM Fragomeni, A Sciallis… - Surgical oncology clinics …, 2018 - pmc.ncbi.nlm.nih.gov
In the era of personalized medicine, there has been significant progress regarding the
molecular analysis of breast cancer subtypes. The major classification schemes are based …

Overall survival with pembrolizumab in early-stage triple-negative breast cancer

P Schmid, J Cortes, R Dent, H McArthur… - … England Journal of …, 2024 - Mass Medical Soc
Background In patients with early-stage triple-negative breast cancer, the phase 3
KEYNOTE-522 trial showed significant improvements in pathological complete response …

Quantitative MRI radiomics in the prediction of molecular classifications of breast cancer subtypes in the TCGA/TCIA data set

H Li, Y Zhu, ES Burnside, E Huang, K Drukker… - NPJ breast …, 2016 - nature.com
Using quantitative radiomics, we demonstrate that computer-extracted magnetic resonance
(MR) image-based tumor phenotypes can be predictive of the molecular classification of …

Breast cancer subtypes and the risk of local and regional relapse

KD Voduc, MCU Cheang, S Tyldesley… - Journal of clinical …, 2010 - ascopubs.org
Purpose The risk of local and regional relapse associated with each breast cancer
molecular subtype was determined in a large cohort of patients with breast cancer. Subtype …

MRI for breast cancer screening, diagnosis, and treatment

M Morrow, J Waters, E Morris - The Lancet, 2011 - thelancet.com
MRI is used widely both for screening women who are at increased risk of breast cancer and
for treatment selection. Prospective studies confirm that MRI screening of women with known …

[HTML][HTML] Triple-negative breast cancer—current status and future directions

O Gluz, C Liedtke, N Gottschalk, L Pusztai, U Nitz… - Annals of …, 2009 - Elsevier
Triple-negative breast cancer (TNBC) is defined by a lack of expression of both estrogen
and progesterone receptor as well as human epidermal growth factor receptor 2. It is …

Locoregional recurrence after breast cancer surgery: a systematic review by receptor phenotype

AJ Lowery, MR Kell, RW Glynn, MJ Kerin… - Breast cancer research …, 2012 - Springer
Molecular subty** confirms that breast cancer comprises at least four genetically distinct
entities based on the expression of specific genes including estrogen receptor (ER) …

Past, present, and future challenges in breast cancer treatment

GW Sledge, EP Mamounas, GN Hortobagyi… - Journal of clinical …, 2014 - ascopubs.org
The past half century—the lifetime of the American Society of Clinical Oncology—represents
a historical watershed in the management of breast cancer, a period in which old dogmas …

[HTML][HTML] Androgen receptor expression in breast cancer in relation to molecular phenotype: results from the Nurses' Health Study

LC Collins, KS Cole, JD Marotti, R Hu, SJ Schnitt… - Modern Pathology, 2011 - Elsevier
Previous studies have demonstrated that androgen receptor is expressed in many breast
cancers, but its expression in relation to the various breast cancer subtypes as defined by …