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[HTML][HTML] Amyloid β, Tau, and α-Synuclein aggregates in the pathogenesis, prognosis, and therapeutics for neurodegenerative diseases
Aggregation of specific proteins are histopathological hallmarks of several
neurodegenerative diseases, such as, Amyloid β (Aβ) plaques and tau neurofibrillary …
neurodegenerative diseases, such as, Amyloid β (Aβ) plaques and tau neurofibrillary …
Chemical design of activatable photoacoustic probes for precise biomedical applications
Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …
integrates the advantage of optical and acoustic imaging, has great application prospects in …
PEP-FOLD4: A pH-dependent force field for peptide structure prediction in aqueous solution
Accurate and fast structure prediction of peptides of less 40 amino acids in aqueous solution
has many biological applications, but their conformations are pH-and salt concentration …
has many biological applications, but their conformations are pH-and salt concentration …
Bioinspired flexible hydrogelation with programmable properties for tactile sensing
Tactile sensing requires integrated detection platforms with distributed and highly sensitive
haptic sensing capabilities along with biocompatibility, aiming to replicate the physiological …
haptic sensing capabilities along with biocompatibility, aiming to replicate the physiological …
In-cell structural biology by NMR: the benefits of the atomic scale
FX Theillet - Chemical reviews, 2022 - ACS Publications
In-cell structural biology aims at extracting structural information about proteins or nucleic
acids in their native, cellular environment. This emerging field holds great promise and is …
acids in their native, cellular environment. This emerging field holds great promise and is …
High-frequency terahertz waves disrupt Alzheimer's β-amyloid fibril formation
W Peng, Z Zhu, J Lou, K Chen, Y Wu, C Chang - eLight, 2023 - Springer
The accumulation and deposition of amyloid can cause a variety of neurodegenerative
diseases, including Alzheimer's and Parkinson's disease. The degradation or clearance of …
diseases, including Alzheimer's and Parkinson's disease. The degradation or clearance of …
Ins and outs of AlphaFold2 transmembrane protein structure predictions
Transmembrane (TM) proteins are major drug targets, but their structure determination, a
prerequisite for rational drug design, remains challenging. Recently, the DeepMind's …
prerequisite for rational drug design, remains challenging. Recently, the DeepMind's …
Imaging amyloid‐β membrane interactions: ion‐channel pores and lipid‐bilayer permeability in Alzheimer's disease
JH Viles - Angewandte Chemie International Edition, 2023 - Wiley Online Library
The accumulation of the amyloid‐β peptides (Aβ) is central to the development of
Alzheimer's disease. The mechanism by which Aβ triggers a cascade of events that leads to …
Alzheimer's disease. The mechanism by which Aβ triggers a cascade of events that leads to …
A hairpin motif in the amyloid-β peptide is important for formation of disease-related oligomers
The amyloid-β (Aβ) peptide is associated with the development of Alzheimer's disease and
is known to form highly neurotoxic prefibrillar oligomeric aggregates, which are difficult to …
is known to form highly neurotoxic prefibrillar oligomeric aggregates, which are difficult to …
C3N nanodots inhibits Aβ peptides aggregation pathogenic path in Alzheimer's disease
X Yin, H Zhou, M Zhang, J Su, X Wang, S Li… - Nature …, 2023 - nature.com
Despite the accumulating evidence linking the development of Alzheimer's disease (AD) to
the aggregation of Aβ peptides and the emergence of Aβ oligomers, the FDA has approved …
the aggregation of Aβ peptides and the emergence of Aβ oligomers, the FDA has approved …