Vitamin B3 (nicotinic acid, niacin) deficiency causes the systemic disease pellagra, which
leads to dermatitis, diarrhea, dementia, and possibly death depending on its severity and …

Background Nicotinamide adenine dinucleotide (NAD+), a critical coenzyme present in
every living cell, is involved in a myriad of metabolic processes associated with cellular …

Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting enzyme in the NAD
salvage pathway of mammalian cells and is overexpressed in numerous types of cancers …

Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinate
phosphoribosyltransferase (NAPRT) are two intracellular enzymes that catalyze the first step …

Cancer cells have a unique energy metabolism for sustaining rapid proliferation. The
preference for anaerobic glycolysis under normal oxygen conditions is a unique trait of …

It is well known that adipokines are endocrine factors that are mainly secreted by white
adipose tissue. Their central role in energy metabolism is currently accepted. More recently …

Nicotinamide adenine dinucleotide (NAD) is a cofactor of many enzymatic reactions as well
as being a substrate for a number of NAD-consuming enzymes (eg, PARPS, sirtuins, etc) …

Nicotinamide (NAM), a form of vitamin B 3, plays essential roles in cell physiology through
facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of …

Background Neutrophils-linked premetastatic niche plays a key role in tumor metastasis, but
not much is known about the heterogeneity and diverse role of neutrophils in niche …

Nicotinamide phosphoribosyl transferase (NAMPT) is considered as a promising target for
cancer therapy given its critical engagement in cancer metabolism and inflammation …