Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

Sepsis remains a leading cause of death worldwide, despite advances in critical care, and
understanding of the pathophysiology and treatment strategies. No specific therapy or drugs …

Background Sepsis is one of the leading causes of death in intensive care unit patients.
Early detection of sepsis is vital because mortality increases as the sepsis stage worsens …

Objective: The aim of this study was to measure neutrophil function longitudinally following
burn injury and to examine the relationship between neutrophil dysfunction and sepsis …

Sepsis represents a life-threatening organ dysfunction due to an aberrant host response. Of
note is that majority of patients have experienced a severe immune depression during and …

In the literature, burns are understood as traumatic events accompanied by increased
morbidity and mortality among affected patients. Their characteristic feature is the formation …

Current methods for the diagnosis of sepsis have insufficient precision, causing regular
misdiagnoses. Microbiological tests can help to diagnose sepsis, but are usually too slow to …

Cells in the body are physically confined by neighboring cells, tissues, and the extracellular
matrix. Although physical confinement modulates intracellular signaling and the underlying …

Sepsis is a life-threatening disease that is associated with organ dysfunction. It occurs due to
the body's dysregulated response to infection. It is difficult to identify sepsis in its early …

Neutrophil swarms protect healthy tissues by sealing off sites of infection. In the absence of
swarming, microbial invasion of surrounding tissues can result in severe infections. Recent …