Immune cell infiltration into solid tumors, their movement within the tumor microenvironment
(TME), and interaction with other immune cells are controlled by their directed migration …

To defense harmful stimuli or maintain the immune homeostasis, the body produces and
recruits a superfamily of cytokines such as interleukins, interferons, chemokines etc. Among …

Abstract Purpose of Review The outbreak of the novel coronavirus disease 2019 (COVID-
19) has emerged to be the biggest global health threat worldwide, which has now infected …

Tumor cells can “hijack” chemokine networks to support tumor progression. In this context,
the CC chemokine ligand 5/CC chemokine receptor type 5 (CCL5/CCR5) axis is gaining …

Vaccine candidates based on spike, the glycoprotein that is essential for host cell entry by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), were being designed …

Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …

Experiments of nature have revealed the peculiar importance of the G-protein–coupled
receptor, CC chemokine receptor type 5 (CCR5), in human disease since ancient times. The …

SARS-CoV-2 is a novel coronavirus that emerged in 2019 and is causing the COVID-19
pandemic. There is no current standard of care. Clinicians need to be mindful of the toxicity …

As the COVID-19 is still growing throughout the globe, a thorough investigation into the
specific immunopathology of SARS-CoV-2, its interaction with the host immune system and …

Chemokines and their corresponding receptors play crucial roles in orchestrating
inflammatory and immune responses, particularly in the context of pathological conditions …