Single-nucleotide-resolution genomic maps of O6-methylguanine from the glioblastoma drug temozolomide

J Kubitschek, V Takhaveev, C Mingard… - Nucleic Acids …, 2025 - academic.oup.com
Temozolomide kills cancer cells by forming O 6-methylguanine (O 6-MeG), which leads to
cell cycle arrest and apoptosis. However, O 6-MeG repair by O 6-methylguanine-DNA …