Allergic rhinitis: a review

JA Bernstein, JS Bernstein, R Makol, S Ward - JAMA, 2024 - jamanetwork.com
Importance Allergic rhinitis affects an estimated 15% of the US population (approximately 50
million individuals) and is associated with the presence of asthma, eczema, chronic or …

Recent advances in the epithelial barrier theory

Y Pat, D Yazici, P D'Avino, M Li, S Ardicli… - International …, 2024 - academic.oup.com
The epithelial barrier theory links the recent rise in chronic non-communicable diseases,
notably autoimmune and allergic disorders, to environmental agents disrupting the epithelial …

Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight

BT Tierney, JK Kim, EG Overbey, KA Ryon, J Foox… - Nature …, 2024 - nature.com
Maintenance of astronaut health during spaceflight will require monitoring and potentially
modulating their microbiomes. However, documenting microbial shifts during spaceflight has …

How does global warming contribute to disorders originating from an impaired epithelial barrier?

C Ozdemir, UC Kucuksezer, I Ogulur, Y Pat… - Annals of Allergy …, 2023 - Elsevier
The epithelial barrier represents the point of contact between the host and the external
environment. It is the first line of defense against external insults in the skin, gastrointestinal …

[HTML][HTML] Vitis vinifera L. Leaf Extract, a Microbiota Green Ally against Infectious and Inflammatory Skin and Scalp Diseases: An In-Depth Update

M Armari, E Zavattaro, CF Trejo, A Galeazzi, A Grossetti… - Antibiotics, 2024 - mdpi.com
The skin microbiota, with its millions of bacteria, fungi, and viruses, plays a key role in
balancing the health of the skin and scalp. Its continuous exposure to potentially harmful …

Epithelial barrier dysfunction and associated diseases in companion animals: Differences and similarities between humans and animals and research needs

S Ardicli, O Ardicli, D Yazici, Y Pat, H Babayev… - Allergy, 2024 - Wiley Online Library
Since the 1960s, more than 350,000 new chemicals have been introduced into the lives of
humans and domestic animals. Many of them have become part of modern life and some …

Deciphering the Interplay between the Epithelial Barrier, Immune Cells, and Metabolic Mediators in Allergic Disease

LLY Kan, P Li, SSM Hon, AYT Lai, A Li… - International Journal of …, 2024 - mdpi.com
Chronic exposure to harmful pollutants, chemicals, and pathogens from the environment can
lead to pathological changes in the epithelial barrier, which increase the risk of develo** …

Probiotics as adjuvants to mitigate adverse reactions and enhance effectiveness in Food Allergy Immunotherapy

I Lamminpää, E Niccolai… - Scandinavian Journal of …, 2024 - Wiley Online Library
In the past decades, food allergies became increasingly dominant since early childhood,
leading to a lower quality of life and to increasing costs addressed by the health care …

[HTML][HTML] Skin as the target for allergy prevention and treatment

A Marques-Mejias, I Bartha, CE Ciaccio… - Annals of Allergy …, 2024 - Elsevier
The fact that genetic and environmental factors could trigger disruption of the epithelial
barrier and subsequently initiate a Th2 inflammatory cascade conversely proposes that …

Lifestyle Changes and Industrialization in the Development of Allergic Diseases

C Ozdemir, UC Kucuksezer, I Ogulur, Y Pat… - Current Allergy and …, 2024 - Springer
Abstract Purpose of Review Modernization and Westernization in industrialized and
develo** nations is associated with a substantial increase in chronic noncommunicable …