The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

Nuclease resistance of DNA nanostructures

AR Chandrasekaran - Nature Reviews Chemistry, 2021 - nature.com
DNA nanotechnology has progressed from proof-of-concept demonstrations of structural
design towards application-oriented research. As a natural material with excellent self …

A DNA nanodevice-based vaccine for cancer immunotherapy

S Liu, Q Jiang, X Zhao, R Zhao, Y Wang, Y Wang… - Nature Materials, 2021 - nature.com
A major challenge in cancer vaccine therapy is the efficient delivery of antigens and
adjuvants to stimulate a controlled yet robust tumour-specific T-cell response. Here, we …

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

S Li, Q Jiang, S Liu, Y Zhang, Y Tian, C Song… - Nature …, 2018 - nature.com
Nanoscale robots have potential as intelligent drug delivery systems that respond to
molecular triggers,,,. Using DNA origami we constructed an autonomous DNA robot …

DNA nanotechnology-enabled drug delivery systems

Q Hu, H Li, L Wang, H Gu, C Fan - Chemical reviews, 2018 - ACS Publications
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

DNA origami: scaffolds for creating higher order structures

F Hong, F Zhang, Y Liu, H Yan - Chemical reviews, 2017 - ACS Publications
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

Multi-micron crisscross structures grown from DNA-origami slats

CM Wintersinger, D Minev, A Ershova… - Nature …, 2023 - nature.com
Living systems achieve robust self-assembly across a wide range of length scales. In the
synthetic realm, nanofabrication strategies such as DNA origami have enabled robust self …

Nonreciprocal lasing in topological cavities of arbitrary geometries

B Bahari, A Ndao, F Vallini, A El Amili, Y Fainman… - Science, 2017 - science.org
Resonant cavities are essential building blocks governing many wave-based phenomena,
but their geometry and reciprocity fundamentally limit the integration of optical devices. We …

Biotechnological mass production of DNA origami

F Praetorius, B Kick, KL Behler, MN Honemann… - Nature, 2017 - nature.com
DNA nanotechnology, in particular DNA origami, enables the bottom-up self-assembly of
micrometre-scale, three-dimensional structures with nanometre-precise features 1, 2, 3, 4, 5 …

Programmable self-assembly of three-dimensional nanostructures from 10,000 unique components

LL Ong, N Hanikel, OK Yaghi, C Grun, MT Strauss… - Nature, 2017 - nature.com
Nucleic acids (DNA and RNA) are widely used to construct nanometre-scale structures with
ever increasing complexity,,,,,,,,,,,,,, with possible application in fields such as structural …