The role of antioxidants in the interplay between oxidative stress and senescence

A Varesi, S Chirumbolo, LIM Campagnoli, E Pierella… - Antioxidants, 2022 - mdpi.com
Cellular senescence is an irreversible state of cell cycle arrest occurring in response to
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …

Advancements in redox-sensitive micelles as nanotheranostics: a new horizon in cancer management

A Sikder, G Vambhurkar, E Amulya… - Journal of Controlled …, 2022 - Elsevier
Abstract World Health Organisation (WHO) delineated cancer as one of the foremost
reasons for mortality with 10 million deaths in the year 2020. Early diagnosis and effective …

Bacterial Metallostasis: Metal Sensing, Metalloproteome Remodeling, and Metal Trafficking

DA Capdevila, JJ Rondón, KA Edmonds… - Chemical …, 2024 - ACS Publications
Transition metals function as structural and catalytic cofactors for a large diversity of proteins
and enzymes that collectively comprise the metalloproteome. Metallostasis considers all …

The elements of life: A biocentric tour of the periodic table

KA Remick, JD Helmann - Advances in microbial physiology, 2023 - Elsevier
Living systems are built from a small subset of the atomic elements, including the bulk
macronutrients (C, H, N, O, P, S) and ions (Mg, K, Na, Ca) together with a small but variable …

Characterization of ancestral Fe/Mn superoxide dismutases indicates their cambialistic origin

R Valenti, J Jabłońska, DS Tawfik - Protein Science, 2022 - Wiley Online Library
Superoxide dismutases (SODs) are critical metalloenzymes mitigating the damages of the
modern oxygenated world. However, the emergence of one family of SODs, the Fe/Mn SOD …

Why is manganese so valuable to bacterial pathogens?

J Čapek, B Večerek - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
Apart from oxygenic photosynthesis, the extent of manganese utilization in bacteria varies
from species to species and also appears to depend on external conditions. This …

Oxidoreductases and metal cofactors in the functioning of the earth

B Hay Mele, M Monticelli, S Leone… - Essays in …, 2023 - portlandpress.com
Life sustains itself using energy generated by thermodynamic disequilibria, commonly
existing as redox disequilibria. Metals are significant players in controlling redox reactions …

Fluorescent Protein-Based Sensors for Detecting Essential Metal Ions across the Tree of Life

GC Jensen, MK Janis, HN Nguyen, OW David… - ACS …, 2024 - ACS Publications
Genetically encoded fluorescent metal ion sensors are powerful tools for elucidating metal
dynamics in living systems. Over the last 25 years since the first examples of genetically …

Cu2-xSe@ Bi2MoO6 nanozyme-based immunoassay for the colorimetric detection of walnut allergen in foods

SS Wang, L Sheng, Y Lu - Food Chemistry, 2025 - Elsevier
In the present study, we developed a nanozyme-based direct competitive immunoassay to
detect walnut allergen (Jug r 4) in foods. Walnut monoclonal antibody (mAb) and Cu 2− x …

Speciomics as a concept involving chemical speciation and omics

MAZ Arruda, JR de Jesus, CA Blindauer… - Journal of Proteomics, 2022 - Elsevier
The study of chemical speciation and the refinement and expansion of omics-based
methods are both consolidated and highly active research fields. Although well established …