The role of antioxidants in the interplay between oxidative stress and senescence
Cellular senescence is an irreversible state of cell cycle arrest occurring in response to
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …
Advancements in redox-sensitive micelles as nanotheranostics: a new horizon in cancer management
A Sikder, G Vambhurkar, E Amulya… - Journal of Controlled …, 2022 - Elsevier
Abstract World Health Organisation (WHO) delineated cancer as one of the foremost
reasons for mortality with 10 million deaths in the year 2020. Early diagnosis and effective …
reasons for mortality with 10 million deaths in the year 2020. Early diagnosis and effective …
Bacterial Metallostasis: Metal Sensing, Metalloproteome Remodeling, and Metal Trafficking
DA Capdevila, JJ Rondón, KA Edmonds… - Chemical …, 2024 - ACS Publications
Transition metals function as structural and catalytic cofactors for a large diversity of proteins
and enzymes that collectively comprise the metalloproteome. Metallostasis considers all …
and enzymes that collectively comprise the metalloproteome. Metallostasis considers all …
The elements of life: A biocentric tour of the periodic table
KA Remick, JD Helmann - Advances in microbial physiology, 2023 - Elsevier
Living systems are built from a small subset of the atomic elements, including the bulk
macronutrients (C, H, N, O, P, S) and ions (Mg, K, Na, Ca) together with a small but variable …
macronutrients (C, H, N, O, P, S) and ions (Mg, K, Na, Ca) together with a small but variable …
Characterization of ancestral Fe/Mn superoxide dismutases indicates their cambialistic origin
R Valenti, J Jabłońska, DS Tawfik - Protein Science, 2022 - Wiley Online Library
Superoxide dismutases (SODs) are critical metalloenzymes mitigating the damages of the
modern oxygenated world. However, the emergence of one family of SODs, the Fe/Mn SOD …
modern oxygenated world. However, the emergence of one family of SODs, the Fe/Mn SOD …
Why is manganese so valuable to bacterial pathogens?
J Čapek, B Večerek - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
Apart from oxygenic photosynthesis, the extent of manganese utilization in bacteria varies
from species to species and also appears to depend on external conditions. This …
from species to species and also appears to depend on external conditions. This …
Oxidoreductases and metal cofactors in the functioning of the earth
Life sustains itself using energy generated by thermodynamic disequilibria, commonly
existing as redox disequilibria. Metals are significant players in controlling redox reactions …
existing as redox disequilibria. Metals are significant players in controlling redox reactions …
Fluorescent Protein-Based Sensors for Detecting Essential Metal Ions across the Tree of Life
Genetically encoded fluorescent metal ion sensors are powerful tools for elucidating metal
dynamics in living systems. Over the last 25 years since the first examples of genetically …
dynamics in living systems. Over the last 25 years since the first examples of genetically …
Cu2-xSe@ Bi2MoO6 nanozyme-based immunoassay for the colorimetric detection of walnut allergen in foods
SS Wang, L Sheng, Y Lu - Food Chemistry, 2025 - Elsevier
In the present study, we developed a nanozyme-based direct competitive immunoassay to
detect walnut allergen (Jug r 4) in foods. Walnut monoclonal antibody (mAb) and Cu 2− x …
detect walnut allergen (Jug r 4) in foods. Walnut monoclonal antibody (mAb) and Cu 2− x …
Speciomics as a concept involving chemical speciation and omics
MAZ Arruda, JR de Jesus, CA Blindauer… - Journal of Proteomics, 2022 - Elsevier
The study of chemical speciation and the refinement and expansion of omics-based
methods are both consolidated and highly active research fields. Although well established …
methods are both consolidated and highly active research fields. Although well established …