Brain disorders represent a significant challenge in medical science due to the formidable
blood–brain barrier (BBB), which severely limits the penetration of conventional …

Sepsis is accompanied by thrombocytopenia and the severity of the thrombocytopenia is
associated with mortality. This thrombocytopenia is characteristic of disseminated …

Inflammatory proteins activate platelets, which have been observed to be directly related to
cancer progression and development. The aim of this systematic review is to investigate the …

The skin's recognised functions may undergo physiological alterations due to ageing,
manifesting as varying degrees of facial wrinkles, diminished tautness, density, and volume …

Uncontrolled bleeding from trauma or surgery remains an important factor affecting the
survival and prognosis of surgical patients. Failure to timeously stop bleeding will not only …

Cancer metastasis, the leading cause of cancer-related deaths, remains a complex
challenge in medical science. Stephen Paget's “seed and soil theory” introduced the …

Alzheimer's disease (AD) and related dementias (ADRD) collectively affect a significant
portion of the aging population worldwide. The pathological progression of AD involves not …

In cancer, activation of platelets by tumor cells is critical to disease progression.
Development of precise antiplatelet targeting may improve outcomes from anticancer …

Background Blood platelets are known to play a role in the development of atherosclerotic
disease, thrombi, and hemostasis. Investigation of blood platelet transcriptome could …

For more than 40 years, autologous platelet concentrates have been used in clinical
medicine. Since the first formula used, namely platelet-rich plasma (PRP), other platelet …