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The immunometabolic reprogramming of microglia in Alzheimerʼs disease
H Chen, Z Guo, Y Sun, X Dai - Neurochemistry international, 2023 - Elsevier
Alzheimer's disease (AD) is an age-related neurodegenerative disorder (NDD). In the
central nervous system (CNS), immune cells like microglia could reprogram intracellular …
central nervous system (CNS), immune cells like microglia could reprogram intracellular …
Regulation of microglia by glutamate and its signal pathway in neurodegenerative diseases
X Zhang, D Wang, B Zhang, J Zhu, Z Zhou, L Cui - Drug discovery today, 2020 - Elsevier
Highlights•Microglia are involved in the pathogenesis of neurodegenerative disorders.•
Microglialdiversity regulated by glutamate plays acrucial role in neurodegenerative …
Microglialdiversity regulated by glutamate plays acrucial role in neurodegenerative …
[HTML][HTML] The role of aldose reductase in beta-amyloid-induced microglia activation
YK Huang, CC Liu, S Wang, HC Cheng… - International Journal of …, 2022 - mdpi.com
The occurrence of Alzheimer's disease has been associated with the accumulation of beta-
amyloid (β-amyloid) plaques. These plaques activate microglia to secrete inflammatory …
amyloid (β-amyloid) plaques. These plaques activate microglia to secrete inflammatory …
[HTML][HTML] Synthesis and evaluation of novel pyrazole ethandiamide compounds as inhibitors of human THP-1 monocytic cell neurotoxicity
JA McKenzie, RF Barghash, AT Alsaggaf, O Kulkarni… - Cells, 2019 - mdpi.com
Neuroinflammation and microglia-mediated neurotoxicity contribute to the pathogenesis of a
broad range of neurodegenerative diseases; therefore, identifying novel compounds that …
broad range of neurodegenerative diseases; therefore, identifying novel compounds that …
[PDF][PDF] Microglia-induced Neurotoxicity: A Review of in Vitro Co-culture Models
NNA Puzi, S Vidyadaran - Malaysian J Med Health Sci, 2020 - psasir.upm.edu.my
Microglia-induced neurotoxicity occurs when inflammation mediated by microglia causes
loss of neuronal structures or functions in the central nervous system implicated in stroke …
loss of neuronal structures or functions in the central nervous system implicated in stroke …