Macrophages are innate immune cells that form a 3D network in all our tissues, where they
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …

Embryo-derived tissue-resident macrophages are the first representatives of the
haematopoietic lineage to emerge in metazoans. In mammals, resident macrophages …

Macrophages represent heterogeneous cell population with important roles in defence
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …

The heterogeneity of tissue macrophages, in health and in disease, has become
increasingly transparent over the last decade. But with the plethora of data comes a natural …

Tumour-associated macrophages are an essential component of the tumour
microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix …

Cytokines mediate cell–cell communication in the immune system and represent important
therapeutic targets,–. A myriad of studies have highlighted their central role in immune …

Since their discovery almost two decades ago, interleukin-17-producing CD4+ T cells (TH17
cells) have been implicated in the pathogenesis of multiple autoimmune and inflammatory …

Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …

Resident macrophages orchestrate homeostatic, inflammatory, and reparative activities. It is
appreciated that different tissues instruct specialized macrophage functions. However …

It is well‏‏ established that macrophages are key regulators of wound healing, displaying
impressive plasticity and an evolving phenotype, from an aggressive pro-inflammatory or" …