Activation of the innate immune system following pattern recognition receptor binding has
emerged as one of the major pathogenic mechanisms in neurodegenerative disease …

Alzheimer's disease (AD) is the leading form of dementia worldwide, but its early detection
and diagnosis remain a challenge. MicroRNAs (miRNAs) are a group of small endogenous …

Toll-like receptors (TLRs) are a collection of pattern recognition sensors that form a first line
of defence by detecting pathogen-or damage-associated molecular patterns and initiating …

Amyotrophic lateral sclerosis (ALS) that comprises sporadic (sALS) and familial (fALS)
cases, is a devastating neurodegenerative disorder characterized by progressive …

Acute Respiratory Distress Syndrome (ARDS) is triggered by a variety of insults, such as
bacterial and viral infections, including SARS-CoV-2, leading to high mortality. In the murine …

MicroRNAs (miRNAs) are the smallest class of noncoding RNAs, which widely exist in
animals and plants. They can inhibit translation or overexpression by combining with mRNA …

The efficacy of neurotherapeutic drugs hinges on their ability to traverse the blood-brain
barrier and access the brain, which is crucial for treating or alleviating neurodegenerative …

We previously showed that hydrogen sulfide (H 2 S) has a neuroprotective effect in the
context of hypoxic ischemic brain injury in neonatal mice. However, the precise mechanism …

Transfer RNA fragments (tRFs) have recently been shown to be an important family of small
regulatory RNAs with diverse functions. Recent reports have revealed modified tRF blood …

We investigated the association between circulating microRNAs (miRNAs) potentially
involved in the lung inflammatory process and fibrosis development among COVID-19 …