Anti-Markovnikov intermolecular hydroamination of alkenes and alkynes: a mechanistic view

J Escorihuela, A Lledós, G Ujaque - Chemical Reviews, 2023 - ACS Publications
Hydroamination, the addition of an N–H bond across a C–C multiple bond, is a reaction with
a great synthetic potential. Important advances have been made in the last decades …

Recent advances in the enantioselective synthesis of chiral amines via transition metal-catalyzed asymmetric hydrogenation

A Cabré, X Verdaguer, A Riera - Chemical Reviews, 2021 - ACS Publications
Chiral amines are key structural motifs present in a wide variety of natural products, drugs,
and other biologically active compounds. During the past decade, significant advances have …

Copper hydride catalyzed hydroamination of alkenes and alkynes

MT Pirnot, YM Wang… - Angewandte Chemie …, 2016 - Wiley Online Library
Over the past few years, CuH‐catalyzed hydroamination has been discovered and
developed as a robust and conceptually novel approach for the synthesis of …

Progression of hydroamination catalyzed by late transition-metal complexes from activated to unactivated alkenes

S Ma, JF Hartwig - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus Catalytic intermolecular hydroamination of alkenes is an atom-and step-
economical method for the synthesis of amines, which have important applications as …

Incorporation of chiral frustrated Lewis pair into metal–organic framework with tailored microenvironment for heterogeneous enantio-and chemoselective …

Y Zhang, Y Jiang, A Nafady, Z Tang… - ACS Central …, 2023 - ACS Publications
The development of efficient heterogeneous catalysts with multiselectivity (eg, enantio-and
chemoselectivity) has long been sought after but with limited progress being made so far. To …

Gold-catalyzed carbon− heteroatom bond-forming reactions

A Corma, A Leyva-Pérez, MJ Sabater - Chemical reviews, 2011 - ACS Publications
After the long-held assumption of the unreactivity of gold, numerous reactions catalyzed by
this noble metal have been increasingly emerging in the literature over the past 2 decades …

Cobalt‐Catalyzed Enantioselective Hydroamination of Arylalkenes with Secondary Amines

H Miao, M Guan, T **ong, G Zhang… - Angewandte Chemie …, 2023 - Wiley Online Library
Catalytic asymmetric hydroamination of alkenes with Lewis basic amines is of great interest
but remains a challenge in synthetic chemistry. Here, we developed a Co‐catalyzed …

Hydroamination: direct addition of amines to alkenes and alkynes

TE Muller, KC Hultzsch, M Yus, F Foubelo… - Chemical …, 2008 - ACS Publications
Nitrogen-containing compounds, such as amines, enamines, and imines, are valuable and
commercially important bulk chemicals, specialty chemicals, and pharmaceuticals. 1 Among …

Counterion effects in homogeneous gold catalysis

M Jia, M Bandini - Acs Catalysis, 2015 - ACS Publications
Homogeneous gold catalysis has received growing attention over the past few years,
enabling the replacement of consolidated organic reactions with more simple, selective, and …

Carbon–heteroatom bond formation catalysed by organometallic complexes

JF Hartwig - Nature, 2008 - nature.com
At one time the synthetic chemist's last resort, reactions catalysed by transition metals are
now the preferred method for synthesizing many types of organic molecule. A recent …