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Anti-Markovnikov intermolecular hydroamination of alkenes and alkynes: a mechanistic view
Hydroamination, the addition of an N–H bond across a C–C multiple bond, is a reaction with
a great synthetic potential. Important advances have been made in the last decades …
a great synthetic potential. Important advances have been made in the last decades …
Recent advances in the enantioselective synthesis of chiral amines via transition metal-catalyzed asymmetric hydrogenation
Chiral amines are key structural motifs present in a wide variety of natural products, drugs,
and other biologically active compounds. During the past decade, significant advances have …
and other biologically active compounds. During the past decade, significant advances have …
Copper hydride catalyzed hydroamination of alkenes and alkynes
MT Pirnot, YM Wang… - Angewandte Chemie …, 2016 - Wiley Online Library
Over the past few years, CuH‐catalyzed hydroamination has been discovered and
developed as a robust and conceptually novel approach for the synthesis of …
developed as a robust and conceptually novel approach for the synthesis of …
Progression of hydroamination catalyzed by late transition-metal complexes from activated to unactivated alkenes
Conspectus Catalytic intermolecular hydroamination of alkenes is an atom-and step-
economical method for the synthesis of amines, which have important applications as …
economical method for the synthesis of amines, which have important applications as …
Incorporation of chiral frustrated Lewis pair into metal–organic framework with tailored microenvironment for heterogeneous enantio-and chemoselective …
The development of efficient heterogeneous catalysts with multiselectivity (eg, enantio-and
chemoselectivity) has long been sought after but with limited progress being made so far. To …
chemoselectivity) has long been sought after but with limited progress being made so far. To …
Gold-catalyzed carbon− heteroatom bond-forming reactions
After the long-held assumption of the unreactivity of gold, numerous reactions catalyzed by
this noble metal have been increasingly emerging in the literature over the past 2 decades …
this noble metal have been increasingly emerging in the literature over the past 2 decades …
Cobalt‐Catalyzed Enantioselective Hydroamination of Arylalkenes with Secondary Amines
H Miao, M Guan, T **ong, G Zhang… - Angewandte Chemie …, 2023 - Wiley Online Library
Catalytic asymmetric hydroamination of alkenes with Lewis basic amines is of great interest
but remains a challenge in synthetic chemistry. Here, we developed a Co‐catalyzed …
but remains a challenge in synthetic chemistry. Here, we developed a Co‐catalyzed …
Hydroamination: direct addition of amines to alkenes and alkynes
Nitrogen-containing compounds, such as amines, enamines, and imines, are valuable and
commercially important bulk chemicals, specialty chemicals, and pharmaceuticals. 1 Among …
commercially important bulk chemicals, specialty chemicals, and pharmaceuticals. 1 Among …
Counterion effects in homogeneous gold catalysis
M Jia, M Bandini - Acs Catalysis, 2015 - ACS Publications
Homogeneous gold catalysis has received growing attention over the past few years,
enabling the replacement of consolidated organic reactions with more simple, selective, and …
enabling the replacement of consolidated organic reactions with more simple, selective, and …
Carbon–heteroatom bond formation catalysed by organometallic complexes
JF Hartwig - Nature, 2008 - nature.com
At one time the synthetic chemist's last resort, reactions catalysed by transition metals are
now the preferred method for synthesizing many types of organic molecule. A recent …
now the preferred method for synthesizing many types of organic molecule. A recent …