Microbiota and the social brain

E Sherwin, SR Bordenstein, JL Quinn, TG Dinan… - Science, 2019 - science.org
BACKGROUND Increasingly, it is recognized that the microbes resident in the
gastrointestinal tract can influence brain physiology and behavior. Research has shown that …

Polyunsaturated fatty acids and their metabolites in brain function and disease

RP Bazinet, S Layé - Nature reviews neuroscience, 2014 - nature.com
The brain is highly enriched with fatty acids. These include the polyunsaturated fatty acids
(PUFAs) arachidonic acid and docosahexaenoic acid, which are largely esterified to the …

Altering the course of schizophrenia: progress and perspectives

MJ Millan, A Andrieux, G Bartzokis… - Nature reviews Drug …, 2016 - nature.com
Despite a lack of recent progress in the treatment of schizophrenia, our understanding of its
genetic and environmental causes has considerably improved, and their relationship to …

Omega-3 polyunsaturated fatty acids critically regulate behaviour and gut microbiota development in adolescence and adulthood

RC Robertson, CS Oriach, K Murphy… - Brain, behavior, and …, 2017 - Elsevier
Background Neurodevelopment is strongly influenced by maternal and early-postnatal diet.
Omega-3 polyunsaturated fatty acids (n-3 PUFA) are vital structural and functional …

Food for mood: relevance of nutritional omega-3 fatty acids for depression and anxiety

T Larrieu, S Layé - Frontiers in physiology, 2018 - frontiersin.org
The central nervous system (CNS) has the highest concentration of lipids in the organism
after adipose tissue. Among these lipids, the brain is particularly enriched with …

Has the time come for a staging model to map the course of eating disorders from high risk to severe enduring illness? An examination of the evidence

J Treasure, D Stein, S Maguire - Early intervention in psychiatry, 2015 - Wiley Online Library
Aim To examine the evidence to support using a staging heuristic for eating disorders,
suggesting that the diagnosis of an eating disorder follows a trajectory across the life course …

Stress and adolescent hippocampal neurogenesis: diet and exercise as cognitive modulators

CM Hueston, JF Cryan, YM Nolan - Translational psychiatry, 2017 - nature.com
Adolescence is a critical period for brain maturation. Deciphering how disturbances to the
central nervous system at this time affect structure, function and behavioural outputs is …

[HTML][HTML] Longer-term outcome in the prevention of psychotic disorders by the Vienna omega-3 study

GP Amminger, MR Schäfer, M Schlögelhofer… - Nature …, 2015 - nature.com
Long-chain omega-3 polyunsaturated fatty acids (PUFAs) are essential for neural
development and function. As key components of brain tissue, omega-3 PUFAs play critical …

EPA is more effective than DHA to improve depression-like behavior, glia cell dysfunction and hippcampal apoptosis signaling in a chronic stress-induced rat model of …

Z Peng, C Zhang, L Yan, Y Zhang, Z Yang… - International journal of …, 2020 - mdpi.com
Clinical evidence indicated that eicosapentaenoic acid (EPA) was more effective than
docosahexaenoic acid (DHA) in depression treatment. However, possible mechanisms …

[HTML][HTML] Lipids in psychiatric disorders and preventive medicine

M Schneider, B Levant, M Reichel, E Gulbins… - Neuroscience & …, 2017 - Elsevier
Psychiatric disorders like mood disorders, schizophrenia, or drug addiction affect a sizeable
proportion of the human population and severely compromise quality of life. Therefore …