[CARTE][B] Stochastic processes in cell biology

PC Bressloff - 2014 - Springer
One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

Phase-space geometry of mass-conserving reaction-diffusion dynamics

F Brauns, J Halatek, E Frey - Physical Review X, 2020 - APS
Experimental studies of protein-pattern formation have stimulated new interest in the
dynamics of reaction-diffusion systems. However, a comprehensive theoretical …

Principles that govern competition or co-existence in Rho-GTPase driven polarization

JG Chiou, SA Ramirez, TC Elston… - PLoS computational …, 2018 - journals.plos.org
Rho-GTPases are master regulators of polarity establishment and cell morphology. Positive
feedback enables concentration of Rho-GTPases into clusters at the cell cortex, from where …

[HTML][HTML] Physics of compartmentalization: How phase separation and signaling shape membrane and organelle identity

E Floris, A Piras, L Dall'Asta, A Gamba, E Hirsch… - Computational and …, 2021 - Elsevier
Compartmentalization of cellular functions is at the core of the physiology of eukaryotic cells.
Recent evidences indicate that a universal organizing process–termed phase separation …

PIP3 waves and PTEN dynamics in the emergence of cell polarity

G Gerisch, B Schroth-Diez, A Müller-Taubenberger… - Biophysical journal, 2012 - cell.com
In a motile eukaryotic cell, front protrusion and tail retraction are superimposed on each
other. To single out mechanisms that result in front to tail or in tail to front transition, we …

A Stochastic Description of Dictyostelium Chemotaxis

G Amselem, M Theves, A Bae, E Bodenschatz, C Beta - PloS one, 2012 - journals.plos.org
Chemotaxis, the directed motion of a cell toward a chemical source, plays a key role in many
essential biological processes. Here, we derive a statistical model that quantitatively …

Forced and spontaneous symmetry breaking in cell polarization

PW Miller, D Fortunato, C Muratov… - Nature computational …, 2022 - nature.com
How does breaking the symmetry of an equation alter the symmetry of its solutions? Here,
we systematically examine how reducing underlying symmetries from spherical to …

Propagating waves separate two states of actin organization in living cells

B Schroth‐Diez, S Gerwig, M Ecke, R Hegerl, S Diez… - HFSP …, 2009 - Taylor & Francis
Propagating actin waves are dynamic supramolecular structures formed by the self‐
assembly of proteins within living cells. They are built from actin filaments together with …

[HTML][HTML] Behavior-induced phase transitions with far from equilibrium patterning in a SIS epidemic model: Global vs non-local feedback

M Banerjee, V Volpert, P Manfredi… - Physica D: Nonlinear …, 2024 - Elsevier
Here, we explore the phase transitions triggered by the implementation of social distancing
in a basic spatiotemporal model of a qualitative SIS-type infectious disease. We consider …

A bistable model of cell polarity

M Semplice, A Veglio, G Naldi, G Serini, A Gamba - PloS one, 2012 - journals.plos.org
Ultrasensitivity, as described by Goldbeter and Koshland, has been considered for a long
time as a way to realize bistable switches in biological systems. It is not as well recognized …