While human regulatory risk assessment (RA) still largely relies on animal studies, new
approach methodologies (NAMs) based on in vitro, in silico or non-mammalian alternative …

Male reproductive development is intricately dependent on fetal androgen action.
Consequently, disrupted androgen action during fetal life can interfere with the development …

Abstract Nafion byproduct 2 (NBP2) is a polyfluoroalkyl ether sulfonic acid that was recently
detected in surface water, drinking water, and human serum samples from monitoring …

Globally, biomonitoring data demonstrate virtually all humans carry residues of multiple per-
and polyfluoroalkyl substances (PFAS). Despite pervasive co-exposure, limited mixtures …

Human male reproductive disorders are common and may have a fetal origin—the testicular
dysgenesis syndrome (TDS) hypothesis. In rats, experimentally induced TDS disorders …

Environmental occurrence and biomonitoring data for per-and polyfluoroalkyl substances
(PFAS) demonstrate that humans are exposed to mixtures of PFAS. This article presents a …

During the population representative German Environmental Survey of Children and
Adolescents (GerES V, 2014–2017) 2256 first-morning void urine samples from 3 to 17 …

Humans carry residues of multiple synthetic chemicals at any given point in time. Research
has demonstrated that compounds with varying molecular initiating events (MIE) that disrupt …

Abstract The European Human Biomonitoring Initiative (HBM4EU) assessed human
biomonitoring data on phthalates in children and adolescents, that were sampled between …

Great attention has been paid in recent years to the harmful effects of various chemicals that
interfere with our natural hormone balance, collectively known as endocrine-disrupting …