[HTML][HTML] COVID-19 and the human innate immune system

JL Schultze, AC Aschenbrenner - Cell, 2021 - cell.com
The introduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the
human population represents a tremendous medical and economic crisis. Innate immunity …

[HTML][HTML] One year into the pandemic: Short-term evolution of SARS-CoV-2 and emergence of new lineages

F González-Candelas, MA Shaw, T Phan… - Infection, Genetics and …, 2021 - Elsevier
The COVID-19 pandemic was officially declared on March 11 th, 2020. Since the very
beginning, the spread of the virus has been tracked nearly in real-time by worldwide …

Three-quarters attack rate of SARS-CoV-2 in the Brazilian Amazon during a largely unmitigated epidemic

LF Buss, CA Prete Jr, CMM Abrahim, A Mendrone Jr… - Science, 2021 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly in Manaus,
the capital of Amazonas state in northern Brazil. The attack rate there is an estimate of the …

Spatiotemporal invasion dynamics of SARS-CoV-2 lineage B. 1.1. 7 emergence

MUG Kraemer, V Hill, C Ruis, S Dellicour, S Bajaj… - Science, 2021 - science.org
Understanding the causes and consequences of the emergence of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants of concern is crucial to pandemic control yet …

An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants

KK Chan, TJC Tan, KK Narayanan, E Procko - Science Advances, 2021 - science.org
The spike S of SARS-CoV-2 recognizes ACE2 on the host cell membrane to initiate entry.
Soluble decoy receptors, in which the ACE2 ectodomain is engineered to block S with high …

Molecular architecture of early dissemination and massive second wave of the SARS-CoV-2 virus in a major metropolitan area

SW Long, RJ Olsen, PA Christensen, DW Bernard… - MBio, 2020 - Am Soc Microbiol
We sequenced the genomes of 5,085 severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) strains causing two coronavirus disease 2019 (COVID-19) disease waves in …

[HTML][HTML] Local Transmission of SARS-CoV-2 Lineage B. 1.1. 7, Brazil, December 2020

IM Claro, FC da Silva Sales, MS Ramundo… - Emerging infectious …, 2021 - ncbi.nlm.nih.gov
In December 2020, research surveillance detected the B. 1.1. 7 lineage of severe acute
respiratory syndrome coronavirus 2 in São Paulo, Brazil. Rapid genomic sequencing and …

Relax, keep walking—a practical guide to continuous phylogeographic inference with BEAST

S Dellicour, MS Gill, NR Faria… - Molecular Biology …, 2021 - academic.oup.com
Spatially explicit phylogeographic analyses can be performed with an inference framework
that employs relaxed random walks to reconstruct phylogenetic dispersal histories in …

[HTML][HTML] Severe acute respiratory syndrome coronavirus 2 P. 2 lineage associated with reinfection case, Brazil, June–October 2020

PC Resende, JF Bezerra… - Emerging infectious …, 2021 - ncbi.nlm.nih.gov
A 37-year-old healthcare worker from the northeastern region of Brazil experienced 2
clinical episodes of coronavirus disease. Infection with severe acute respiratory syndrome …

[HTML][HTML] Use of genomics to track coronavirus disease outbreaks, New Zealand

JL Geoghegan, J Douglas, X Ren… - Emerging Infectious …, 2021 - ncbi.nlm.nih.gov
Real-time genomic sequencing has played a major role in tracking the global spread of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), contributing greatly to …