Pore-forming toxins (PFTs) are virulence factors produced by many pathogenic bacteria and
have long fascinated structural biologists, microbiologists and immunologists. Interestingly …

Colicins are proteins produced by and toxic for some strains of Escherichia coli. They are
produced by strains of E. coli carrying a colicinogenic plasmid that bears the genetic …

Enterobacteriaceae are widely present in many environments related to humans, including
the human body and the food that they consume, from both plant or animal origin. Hence …

Publisher Summary This chapter describes the present state of the studies of the molten
globule state and its role in protein folding and physiological processes. Recent data on the …

The unifying feature of all proteins that are transported out of the cytoplasm of gram-negative
bacteria by the general secretory pathway (GSP) is the presence of a long stretch of …

Bacillus thuringiensis produces crystalline protein inclusions with insecticidal or nematocidal
properties. These crystal (Cry) proteins determine a particular strain's toxicity profile …

The structure of the δ-endotoxin from Bacillus thuringiensis subsp. tenebrionis that is
specifically toxic to Coleopterajnsects (beetle toxin) has been determined at 2.5 Å resolution …

Botulinum neurotoxin type A (BoNT/A) is the potent disease agent in botulism, a potential
biological weapon and an effective therapeutic drug for involuntary muscle disorders. The …

The crystal structure of the diphtheria toxin dimer at 2.5 Å resolution reveals a Y-shaped
molecule of three domains. The catalytic domain, called fragment A, is of the α+ β type …

Pore-forming protein toxins (PFTs) are one of Nature's most potent biological weapons. An
essential feature of their toxicity is the remarkable property that PFTs can exist either in a …