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Assessments of dentate gyrus function: discoveries and debates
M Borzello, S Ramirez, A Treves, I Lee… - Nature Reviews …, 2023 - nature.com
There has been considerable speculation regarding the function of the dentate gyrus (DG)—
a subregion of the mammalian hippocampus—in learning and memory. In this Perspective …
a subregion of the mammalian hippocampus—in learning and memory. In this Perspective …
Adult hippocampal neurogenesis and cognitive flexibility—linking memory and mood
Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …
Regulation and function of adult neurogenesis: from genes to cognition
JB Aimone, Y Li, SW Lee… - Physiological …, 2014 - journals.physiology.org
Adult neurogenesis in the hippocampus is a notable process due not only to its uniqueness
and potential impact on cognition but also to its localized vertical integration of different …
and potential impact on cognition but also to its localized vertical integration of different …
New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?
The integration of adult-born neurons into the circuitry of the adult hippocampus suggests an
important role for adult hippocampal neurogenesis in learning and memory, but its specific …
important role for adult hippocampal neurogenesis in learning and memory, but its specific …
Decay happens: the role of active forgetting in memory
O Hardt, K Nader, L Nadel - Trends in cognitive sciences, 2013 - cell.com
Although the biological bases of forgetting remain obscure, the consensus among cognitive
psychologists emphasizes interference processes, rejecting decay in accounting for memory …
psychologists emphasizes interference processes, rejecting decay in accounting for memory …
[HTML][HTML] Mechanisms and functional implications of adult neurogenesis
C Zhao, W Deng, FH Gage - Cell, 2008 - cell.com
The generation of new neurons is sustained throughout adulthood in the mammalian brain
due to the proliferation and differentiation of adult neural stem cells. In this review, we …
due to the proliferation and differentiation of adult neural stem cells. In this review, we …
Resolving new memories: a critical look at the dentate gyrus, adult neurogenesis, and pattern separation
Recently, investigation of new neurons in memory formation has focused on a specific
function—pattern separation. However, it has been difficult to reconcile the form of …
function—pattern separation. However, it has been difficult to reconcile the form of …
Adult hippocampal neurogenesis in depression
The development of new treatments for depression is predicated upon identification of
neural substrates and mechanisms that underlie its etiology and pathophysiology. The …
neural substrates and mechanisms that underlie its etiology and pathophysiology. The …
Remembering the past and imagining the future: a neural model of spatial memory and imagery.
The authors model the neural mechanisms underlying spatial cognition, integrating
neuronal systems and behavioral data, and address the relationships between long-term …
neuronal systems and behavioral data, and address the relationships between long-term …
Adult neurogenesis and functional plasticity in neuronal circuits
The adult brain is a plastic place. To ensure that the mature nervous system's control of
behaviour is flexible in the face of a varying environment, morphological and physiological …
behaviour is flexible in the face of a varying environment, morphological and physiological …