Genome engineering with targetable nucleases
D Carroll - Annual review of biochemistry, 2014 - annualreviews.org
Current technology enables the production of highly specific genome modifications with
excellent efficiency and specificity. Key to this capability are targetable DNA cleavage …
excellent efficiency and specificity. Key to this capability are targetable DNA cleavage …
[HTML][HTML] Origins of programmable nucleases for genome engineering
S Chandrasegaran, D Carroll - Journal of molecular biology, 2016 - Elsevier
Genome engineering with programmable nucleases depends on cellular responses to a
targeted double-strand break (DSB). The first truly targetable reagents were the zinc finger …
targeted double-strand break (DSB). The first truly targetable reagents were the zinc finger …
Production of hornless dairy cattle from genome-edited cell lines
480 VOLUME 34 NUMBER 5 MAY 2016 NATURE BIOTECHNOLOGY confirmed the
homozygous introgression of PC into RCI-001, RCI-002 (named Spotigy) and RCI-003 …
homozygous introgression of PC into RCI-001, RCI-002 (named Spotigy) and RCI-003 …
Genomic selection in dairy cattle: the USDA experience
Genomic selection has revolutionized dairy cattle breeding. Since 2000, assays have been
developed to genotype large numbers of single-nucleotide polymorphisms (SNPs) at …
developed to genotype large numbers of single-nucleotide polymorphisms (SNPs) at …
Genome edited sheep and cattle
Genome editing tools enable efficient and accurate genome manipulation. An enhanced
ability to modify the genomes of livestock species could be utilized to improve disease …
ability to modify the genomes of livestock species could be utilized to improve disease …
Efficient nonmeiotic allele introgression in livestock using custom endonucleases
We have expanded the livestock gene editing toolbox to include transcription activator-like
(TAL) effector nuclease (TALEN)-and clustered regularly interspaced short palindromic …
(TAL) effector nuclease (TALEN)-and clustered regularly interspaced short palindromic …
Nanobiomaterial vectors for improving gene editing and gene therapy
SW Hu, T Ding, H Tang, H Guo, W Cui, Y Shu - Materials Today, 2023 - Elsevier
With the development of genome editing techniques, gene therapy is becoming a viable
option for the treatment of a variety of human diseases. Genome editing techniques mainly …
option for the treatment of a variety of human diseases. Genome editing techniques mainly …
Synergistic power of genomic selection, assisted reproductive technologies, and gene editing to drive genetic improvement of cattle
Genetic improvement of cattle around the globe has been, and will continue to be, an
important driver of animal agriculture sustainability. There are several reproductive and …
important driver of animal agriculture sustainability. There are several reproductive and …
TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis
H Wu, Y Wang, Y Zhang, M Yang… - Proceedings of the …, 2015 - National Acad Sciences
Transcription activator-like effector nuclease (TALEN)-mediated genome modification has
been applied successfully to create transgenic animals in various species, such as mouse …
been applied successfully to create transgenic animals in various species, such as mouse …
Reproductive technologies in farm animals
I Gordon - 2017 - books.google.com
Building on the successful structure of the first edition, the second edition of Reproductive
Technologies in Farm Animals has been totally updated and revised to provide an up to date …
Technologies in Farm Animals has been totally updated and revised to provide an up to date …