Interneuron cell types are fit to function

A Kepecs, G Fishell - Nature, 2014 - nature.com
Understanding brain circuits begins with an appreciation of their component parts—the cells.
Although GABAergic interneurons are a minority population within the brain, they are crucial …

Disinhibition, a circuit mechanism for associative learning and memory

JJ Letzkus, SBE Wolff, A Lüthi - Neuron, 2015 - cell.com
Although a wealth of data have elucidated the structure and physiology of neuronal circuits,
we still only have a very limited understanding of how behavioral learning is implemented at …

[HTML][HTML] A cortical circuit for gain control by behavioral state

Y Fu, JM Tucciarone, JS Espinosa, N Sheng, DP Darcy… - Cell, 2014 - cell.com
The brain's response to sensory input is strikingly modulated by behavioral state. Notably,
the visual response of mouse primary visual cortex (V1) is enhanced by locomotion, a …

Cortical interneurons that specialize in disinhibitory control

HJ Pi, B Hangya, D Kvitsiani, JI Sanders, ZJ Huang… - Nature, 2013 - nature.com
In the mammalian cerebral cortex the diversity of interneuronal subtypes underlies a division
of labour subserving distinct modes of inhibitory control,,,,,,. A unique mode of inhibitory …

[HTML][HTML] Prediction and memory: A predictive coding account

HC Barron, R Auksztulewicz, K Friston - Progress in neurobiology, 2020 - Elsevier
The hippocampus is crucial for episodic memory, but it is also involved in online prediction.
Evidence suggests that a unitary hippocampal code underlies both episodic memory and …

Cellular mechanisms of brain state–dependent gain modulation in visual cortex

PO Polack, J Friedman, P Golshani - Nature neuroscience, 2013 - nature.com
Visual cortical neurons fire at higher rates to visual stimuli during locomotion than during
immobility, while maintaining orientation selectivity. The mechanisms underlying this change …

[HTML][HTML] Central cholinergic neurons are rapidly recruited by reinforcement feedback

B Hangya, SP Ranade, M Lorenc, A Kepecs - Cell, 2015 - cell.com
Basal forebrain cholinergic neurons constitute a major neuromodulatory system implicated
in normal cognition and neurodegenerative dementias. Cholinergic projections densely …

Interneuron types as attractors and controllers

G Fishell, A Kepecs - Annual review of neuroscience, 2020 - annualreviews.org
Cortical interneurons display striking differences in shape, physiology, and other attributes,
challenging us to appropriately classify them. We previously suggested that interneuron …

Structure and function of axo-axonic inhibition

CM Schneider-Mizell, AL Bodor, F Collman, D Brittain… - Elife, 2021 - elifesciences.org
Inhibitory neurons in mammalian cortex exhibit diverse physiological, morphological,
molecular, and connectivity signatures. While considerable work has measured the average …

Vasoactive intestinal polypeptide-expressing interneurons in the hippocampus support goal-oriented spatial learning

GF Turi, WK Li, S Chavlis, I Pandi, J O'Hare… - Neuron, 2019 - cell.com
Diverse computations in the neocortex are aided by specialized GABAergic interneurons
(INs), which selectively target other INs. However, much less is known about how these …