Two major functions of the mammalian ovary are the production of germ cells (oocytes),
which allow continuation of the species, and the generation of bioactive molecules, primarily …

Reproduction is required for the survival of all mammalian species, and thousands of
essential'sex'genes are conserved through evolution. Basic research helps to define these …

Before ovulation in mammals, a cascade of events resembling an inflammatory and/or tissue
remodeling process is triggered by luteinizing hormone (LH) in the ovarian follicle. Many LH …

Human Blepharophimosis/ptosis/epicanthus inversus syndrome (BPES) type I is an
autosomal dominant disorder associated with premature ovarian failure (POF) caused by …

Primary ovarian insufficiency (POI) affects∼ 1% of women before 40 years of age. The
recent leap in genetic knowledge obtained by next generation sequencing (NGS) together …

Infertility is defined as a failure to conceive in a couple trying to reproduce for a period of two
years without conception. Approximately 15 percent of couples are infertile, and among …

For over 40 years, Yen & Jaffe's Reproductive Endocrinology has been the gold standard
text of both basic science and clinical practice of the full range of female and male …