The role of non-coding RNAs in oncology
For decades, research into cancer biology focused on the involvement of protein-coding
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …
MicroRNAs: new biomarkers for diagnosis, prognosis, therapy prediction and therapeutic tools for breast cancer
Dysregulation of microRNAs (miRNAs) is involved in the initiation and progression of
several human cancers, including breast cancer (BC), as strong evidence has been found …
several human cancers, including breast cancer (BC), as strong evidence has been found …
MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy
In normal cells multiple microRNAs (miRNAs) converge to maintain a proper balance of
various processes, including proliferation, differentiation and cell death. miRNA …
various processes, including proliferation, differentiation and cell death. miRNA …
Epigenetic regulation in hematopoiesis and its implications in the targeted therapy of hematologic malignancies
A Zhao, H Zhou, J Yang, M Li, T Niu - Signal transduction and targeted …, 2023 - nature.com
Hematologic malignancies are one of the most common cancers, and the incidence has
been rising in recent decades. The clinical and molecular features of hematologic …
been rising in recent decades. The clinical and molecular features of hematologic …
The miR-29 family: genomics, cell biology, and relevance to renal and cardiovascular injury
AJ Kriegel, Y Liu, Y Fang, X Ding… - Physiological …, 2012 - journals.physiology.org
The human miR-29 family of microRNAs has three mature members, miR-29a, miR-29b, and
miR-29c. miR-29s are encoded by two gene clusters. Binding sites for several transcriptional …
miR-29c. miR-29s are encoded by two gene clusters. Binding sites for several transcriptional …
Virus-encoded microRNAs: an overview and a look to the future
RP Kincaid, CS Sullivan - PLoS pathogens, 2012 - journals.plos.org
MicroRNAs (miRNAs) are small RNAs that play important roles in the regulation of gene
expression. First described as posttranscriptional gene regulators in eukaryotic hosts, virus …
expression. First described as posttranscriptional gene regulators in eukaryotic hosts, virus …
Clinical applications for microRNAs in cancer
SP Nana‐Sinkam, CM Croce - Clinical Pharmacology & …, 2013 - Wiley Online Library
The discovery that noncoding components of the genome, including microRNA (miRNA or
miR), can contribute to the pathogenesis of cancer has led investigators to contemplate …
miR), can contribute to the pathogenesis of cancer has led investigators to contemplate …
The viral and cellular microRNA targetome in lymphoblastoid cell lines
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell
cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral …
cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral …
MicroRNAs in B-cell lymphomas: how a complex biology gets more complex
K Musilová, M Mráz - Leukemia, 2015 - nature.com
MicroRNAs (miRNAs) represent important regulators of gene expression besides
transcriptional control. miRNA regulation can be involved in the cell developmental fate …
transcriptional control. miRNA regulation can be involved in the cell developmental fate …
The role of miR-29b in cancer: regulation, function, and signaling
B Yan, Q Guo, F Fu, Z Wang, Z Yin, Y Wei… - OncoTargets and …, 2015 - Taylor & Francis
MicroRNAs (miRNAs) are endogenous small non-coding RNAs with the capacity to regulate
gene expression post-transcriptionally. The miRNA-29 family consists of miR-29a, miR-29b …
gene expression post-transcriptionally. The miRNA-29 family consists of miR-29a, miR-29b …