The firmicutes/bacteroidetes ratio: a relevant marker of gut dysbiosis in obese patients?

F Magne, M Gotteland, L Gauthier, A Zazueta, S Pesoa… - Nutrients, 2020 - mdpi.com
The gut microbiota is emerging as a promising target for the management or prevention of
inflammatory and metabolic disorders in humans. Many of the current research efforts are …

Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics

P Song, LR Wu, YH Yan, JX Zhang, T Chu… - Nature biomedical …, 2022 - nature.com
Cell-free DNA (cfDNA) in the circulating blood plasma of patients with cancer contains
tumour-derived DNA sequences that can serve as biomarkers for guiding therapy, for the …

Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2's q2-feature-classifier plugin

NA Bokulich, BD Kaehler, JR Rideout, M Dillon… - Microbiome, 2018 - Springer
Background Taxonomic classification of marker-gene sequences is an important step in
microbiome analysis. Results We present q2-feature-classifier (https://github. com/qiime2/q2 …

Soil pH mediates the balance between stochastic and deterministic assembly of bacteria

BM Tripathi, JC Stegen, M Kim, K Dong… - The ISME …, 2018 - academic.oup.com
Little is known about the factors affecting the relative influences of stochastic and
deterministic processes that govern the assembly of microbial communities in successional …

An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar

ND Grubaugh, K Gangavarapu, J Quick, NL Matteson… - Genome biology, 2019 - Springer
How viruses evolve within hosts can dictate infection outcomes; however, reconstructing this
process is challenging. We evaluate our multiplexed amplicon approach, PrimalSeq, to …

Revisiting plant–microbe interactions and microbial consortia application for enhancing sustainable agriculture: a review

K Vishwakarma, N Kumar, C Shandilya… - Frontiers in …, 2020 - frontiersin.org
The present scenario of agricultural sector is dependent hugely on the use of chemical-
based fertilizers and pesticides that impact the nutritional quality, health status, and …

UNOISE2: improved error-correction for Illumina 16S and ITS amplicon sequencing

RC Edgar - BioRxiv, 2016 - biorxiv.org
Amplicon sequencing of tags such as 16S and ITS ribosomal RNA is a popular method for
investigating microbial populations. In such experiments, sequence errors caused by PCR …

DNA metabarcoding—Need for robust experimental designs to draw sound ecological conclusions

L Zinger, A Bonin, IG Alsos, M Bálint, H Bik… - Molecular …, 2019 - Wiley Online Library
DNA metabarcoding, especially when coupled with high‐through‐put DNA sequencing, is
currently revolutionizing our capacity to assess biodiversity across a full range of taxa and …

[HTML][HTML] The future of biotic indices in the ecogenomic era: Integrating (e) DNA metabarcoding in biological assessment of aquatic ecosystems

J Pawlowski, M Kelly-Quinn, F Altermatt… - Science of the Total …, 2018 - Elsevier
The bioassessment of aquatic ecosystems is currently based on various biotic indices that
use the occurrence and/or abundance of selected taxonomic groups to define ecological …

UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy

T Smith, A Heger, I Sudbery - Genome research, 2017 - genome.cshlp.org
Unique Molecular Identifiers (UMIs) are random oligonucleotide barcodes that are
increasingly used in high-throughput sequencing experiments. Through a UMI, identical …