Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies

DP Finn, S Haroutounian, AG Hohmann, E Krane… - Pain, 2021‏ - journals.lww.com
This narrative review represents an output from the International Association for the Study of
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …

Diversity of molecular targets and signaling pathways for CBD

DL de Almeida, LA Devi - Pharmacology research & …, 2020‏ - Wiley Online Library
Cannabidiol (CBD) is the second most abundant component of the Cannabis plant and is
known to have effects distinct from Δ9‐tetrahydrocannabinol (THC). Many studies that …

An update on safety and side effects of cannabidiol: a review of clinical data and relevant animal studies

K Iffland, F Grotenhermen - Cannabis and cannabinoid research, 2017‏ - liebertpub.com
Introduction: This literature survey aims to extend the comprehensive survey performed by
Bergamaschi et al. in 2011 on cannabidiol (CBD) safety and side effects. Apart from …

Cannabidiol for the reduction of cue-induced craving and anxiety in drug-abstinent individuals with heroin use disorder: a double-blind randomized placebo-controlled …

YL Hurd, S Spriggs, J Alishayev… - American Journal of …, 2019‏ - psychiatryonline.org
Objective: Despite the staggering consequences of the opioid epidemic, limited nonopioid
medication options have been developed to treat this medical and public health crisis. This …

[HTML][HTML] Clinicians' guide to cannabidiol and hemp oils

HJ VanDolah, BA Bauer, KF Mauck - Mayo Clinic Proceedings, 2019‏ - Elsevier
Cannabidiol (CBD) oils are low tetrahydrocannabinol products derived from Cannabis sativa
that have become very popular over the past few years. Patients report relief for a variety of …

Cannabis, cannabinoids, and health

G Lafaye, L Karila, L Blecha… - Dialogues in clinical …, 2017‏ - Taylor & Francis
Cannabis (also known as marijuana) is the most frequently used illicit psychoactive
substance in the world. Though it was long considered to be a “soft” drug, studies have …

Cannabidiol (CBD) use in psychiatric disorders: A systematic review

S Bonaccorso, A Ricciardi, C Zangani, S Chiappini… - Neurotoxicology, 2019‏ - Elsevier
Abstract Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the most represented
phytocannabinoids in Cannabis sativa plants. However, CBD may present with a different …

Evaluation of the effects of CBD hemp extract on opioid use and quality of life indicators in chronic pain patients: a prospective cohort study

A Capano, R Weaver, E Burkman - Postgraduate medicine, 2020‏ - Taylor & Francis
Context: Chronic pain is highly prevalent in most of the industrialized nations around the
world. Despite the documented adverse effects, opioids are widely used for pain …

Therapeutic efficacy of cannabidiol (CBD): a review of the evidence from clinical trials and human laboratory studies

DJ Sholler, L Schoene, TR Spindle - Current addiction reports, 2020‏ - Springer
Rigorous, controlled evidence for the therapeutic efficacy of CBD is lacking for many health
conditions. Possible concerns with the use of CBD as a therapeutic include the potential for …

Emerging evidence for cannabis' role in opioid use disorder

B Wiese, AR Wilson-Poe - Cannabis and cannabinoid research, 2018‏ - liebertpub.com
Introduction: The opioid epidemic has become an immense problem in North America, and
despite decades of research on the most effective means to treat opioid use disorder (OUD) …