Mucosal-associated invariant T (MAIT) cells have been attracting increasing attention over
the last few years as a potent unconventional T cell subset. Three factors largely account for …

CXCL16 is a chemotactic cytokine belonging to the α-chemokine subfamily. It plays a
significant role in the progression of cancer, as well as the course of atherosclerosis, renal …

Background & Aims Despite recent translation of immunotherapies into clinical practice, the
immunobiology of hepatocellular carcinoma (HCC), in particular the role and clinical …

Resident memory T cells (TRM cells) are an important first-line defense against respiratory
pathogens, but the unique contributions of lung TRM cell populations to protective immunity …

Mucosal-associated invariant T (MAIT) cells are very abundant in humans and have
antimicrobial specificity, but their functions remain unclear. MAIT cells are CD161hiIL-18Rα+ …

Hepatic natural killer (NK) cells mediate antigen-specific contact hypersensitivity (CHS) in
mice deficient in T cells and B cells. We report here that hepatic NK cells, but not splenic or …

Recruitment of effector T cells to inflamed peripheral tissues is regulated by chemokines and
their receptors, but the factors regulating recruitment to tumors remain largely undefined …

Background Emerging RNA viruses that target the central nervous system (CNS) lead to
cognitive sequelae in survivors. Studies in humans and mice infected with West Nile virus …

Liver sinusoidal endothelial cells (LSEC) form a unique barrier between the liver sinusoids
and the underlying parenchyma, and thus play a crucial role in maintaining metabolic and …

Human mucosal-associated invariant T (MAIT) cells are characterized by their expression of
an invariant TCR α chain Vα7. 2-Jα33/Jα20/Jα12 paired with a restricted TCR β chain. MAIT …