Emerging evidence for adapting radiotherapy to immunotherapy
L Galluzzi, MJ Aryankalayil, CN Coleman… - Nature reviews Clinical …, 2023 - nature.com
Immunotherapy has revolutionized the clinical management of many malignancies but is
infrequently associated with durable objective responses when used as a standalone …
infrequently associated with durable objective responses when used as a standalone …
Killing two birds with one stone: Abscopal effect mechanism and its application prospect in radiotherapy
B Yu, Y Gao, J Li, F Gao, J Zhang, L Li, X Feng… - Critical Reviews in …, 2024 - Elsevier
Abscopal effects are characterized by the emergence of neoplasms in regions unrelated to
the primary radiation therapy site, displaying a gradual attenuation or regression throughout …
the primary radiation therapy site, displaying a gradual attenuation or regression throughout …
Synergistic local combination of radiation and anti-programmed death ligand 1 immunotherapy using radiation-responsive splintery metallic nanocarriers
Radiation therapy (RT)-mediated tumor immunogenicity offers an opportunity for synergistic
combination RT and immunotherapy. One of the challenges in the clinic is to attain the …
combination RT and immunotherapy. One of the challenges in the clinic is to attain the …
[HTML][HTML] A patient-level data meta-analysis of the abscopal effect
Purpose The abscopal effect is defined when a form of local therapy causes tumor
regression of both the target lesion and any untreated tumors. Herein cases of the abscopal …
regression of both the target lesion and any untreated tumors. Herein cases of the abscopal …
Impact of proton therapy on antitumor immune response
Radiotherapy delivered using photons induces an immune response that leads to
modulation of the tumor microenvironment. Clinical studies are ongoing to evaluate immune …
modulation of the tumor microenvironment. Clinical studies are ongoing to evaluate immune …
Gastric cancer with brain metastasis: from molecular characteristics and treatment
Y Zhu, M Zhou, C Li, W Kong, Y Hu - Frontiers in Oncology, 2024 - frontiersin.org
Gastric cancer is one of the cancers with increasing incidence and ranks fourth globally
among the most frequent causes of cancer-related mortality. Early gastric cancer is often …
among the most frequent causes of cancer-related mortality. Early gastric cancer is often …
Immunostimulatory effects of radiotherapy for local and systemic control of melanoma: A review
J Takahashi, S Nagasawa - International journal of molecular sciences, 2020 - mdpi.com
Recently, modern therapies involving immune checkpoint inhibitors, cytokines, and oncolytic
virus have been developed. Because of the limited treatment effect of modern therapy alone …
virus have been developed. Because of the limited treatment effect of modern therapy alone …
Charged particle and conventional radiotherapy: current implications as partner for immunotherapy
D Marcus, RIY Lieverse, C Klein, A Abdollahi… - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapy provides the unprecedented opportunity to prolong the
survival of cancer patients and even cure patients with previously untreatable malignancies …
survival of cancer patients and even cure patients with previously untreatable malignancies …
[HTML][HTML] Phase II trial of combined durvalumab plus tremelimumab with proton therapy for recurrent or metastatic head and neck squamous cell carcinoma
H Kim, S Park, HA Jung, SH Lee… - … : Official Journal of …, 2023 - synapse.koreamed.org
Purpose This phase II study investigated whether durvalumab/tremelimumab with proton
therapy improves the objective response rate (ORR), overall survival (OS), and progression …
therapy improves the objective response rate (ORR), overall survival (OS), and progression …
Multi‐institutional analysis of stereotactic body radiotherapy for sarcoma pulmonary metastases: high rates of local control with favorable toxicity
BC Baumann, KDA Bernstein… - Journal of surgical …, 2020 - Wiley Online Library
Abstract Background/Objectives Oligometastatic sarcoma pulmonary metastases (PM's) are
traditionally treated with resection and/or chemotherapy. We hypothesize that stereotactic …
traditionally treated with resection and/or chemotherapy. We hypothesize that stereotactic …