▪ Abstract The principles underlying regeneration in planarians have been explored for over
100 years through surgical manipulations and cellular observations. Planarian regeneration …

Having an almost unlimited capacity to regenerate tissues lost to age and injury, planarians
have long fascinated naturalists. In the Western hemisphere alone, their documented history …

We have developed a portable and easily configurable genome annotation pipeline called
MAKER. Its purpose is to allow investigators to independently annotate eukaryotic genomes …

Abstract Background The freshwater planarian Schmidtea mediterranea has emerged as a
powerful model for studies of regenerative, stem cell, and germ cell biology. Whole-mount in …

In adult planarians, the replacement of cells lost to physiological turnover or injury is
sustained by the proliferation and differentiation of stem cells known as neoblasts. Neoblast …

Regeneration is widespread throughout the animal kingdom, but our molecular
understanding of this process in adult animals remains poorly understood. Wnt/β-catenin …

The great powers of regeneration shown by freshwater planarians, capable of regenerating
a complete organism from any tiny body fragment, have attracted the interest of scientists …

Planarians can be cut into irregularly shaped fragments capable of regenerating new and
complete organisms. Such regenerative capacities involve a robust ability to restore bilateral …

In contrast to most adult organisms, freshwater planarians can regenerate any injured body
part, including their entire nervous system. This allows for the analysis of genes required for …

The regulation of scale and proportion in living organisms is an intriguing and enduring
problem of biology. Regulatory mechanisms for controlling body size and proportion are …