Unsustainable plastic production, use and mismanagement has resulted in increased global
plastic pollution and subsequent degradation into micro (nano) plastics in the environment …

The concept of one health highlights that human health is not isolated but connected to the
health of animals, plants and environments. In this Review, we demonstrate that soils are a …

This planetary boundaries framework update finds that six of the nine boundaries are
transgressed, suggesting that Earth is now well outside of the safe operating space for …

The stability and resilience of the Earth system and human well-being are inseparably
linked,–, yet their interdependencies are generally under-recognized; consequently, they …

It is hypothesized that environmental contamination by per-and polyfluoroalkyl substances
(PFAS) defines a separate planetary boundary and that this boundary has been exceeded …

Green water—terrestrial precipitation, evaporation and soil moisture—is fundamental to
Earth system dynamics and is now extensively perturbed by human pressures at continental …

Climate change, biodiversity loss and pollution—the triple planetary crisis—increasingly
threaten the Earth system, necessitating tools such as life-cycle assessment (LCA) that can …

Background: Plastics have conveyed great benefits to humanity and made possible some of
the most significant advances of modern civilization in fields as diverse as medicine …

Background Per-and polyfluorinated alkyl substances (PFAS) have received increasing
scientific and political attention in recent years. Several thousand commercially produced …

Highlights•Autoimmunity is defined by a self-reactive adaptive immune system, causing
clinical pathology in autoimmune diseases.•Evidence suggests that autoimmunity and …