[HTML][HTML] Melanoma-derived extracellular vesicles transfer proangiogenic factors

M Wilczak, M Surman, M PRZYBYłO - Oncology research, 2025 - pmc.ncbi.nlm.nih.gov
Angiogenesis, the expansion of pre-existing vascular networks, is crucial for normal organ
growth and tissue repair, but is also involved in various pathologies, including inflammation …

Incorporation of immunotherapies and nanomedicine to better normalize angiogenesis-based cancer treatment

SA Jasim, IM Farber, SAM Noraldeen, P Bansal… - Microvascular …, 2024 - Elsevier
Neoadjuvant targeting of tumor angiogenesis has been developed and approved for the
treatment of malignant tumors. However, vascular disruption leads to tumor hypoxia, which …

Clinical applicability and cost of a 46-gene panel for genomic analysis of solid tumours: Retrospective validation and prospective audit in the UK National Health …

A Hamblin, S Wordsworth, JM Fermont, S Page… - PLoS …, 2017 - journals.plos.org
Background Single gene tests to predict whether cancers respond to specific targeted
therapies are performed increasingly often. Advances in sequencing technology, collectively …

[HTML][HTML] Novel prognostic immunohistochemical markers in uveal melanoma-literature review

M Gajdzis, R Kaczmarek, P Gajdzis - Cancers, 2021 - mdpi.com
Simple Summary The following study provides an overview of the English-language
literature on the search for new prognostic factors for uveal melanoma. Uveal melanoma is …

Small molecule drugs and targeted therapy for melanoma: current strategies and future directions

C Cerchia, A Lavecchia - Current medicinal chemistry, 2017 - benthamdirect.com
Malignant melanoma is the most aggressive and life-threatening skin cancer. Melanoma
develops in melanocytes and is characterized by a very high tendency to spread to other …

Tape stripped stratum corneum samples prove to be suitable for comprehensive proteomic investigation of actinic keratosis

A Azimi, M Ali, KL Kaufman, GJ Mann… - PROTEOMICS …, 2019 - Wiley Online Library
Purpose Actinic keratoses (AK) are premalignant tumors that can be clinically difficult to
differentiate from skin cancer. An easy, quick, and reliable noninvasive alternative to biopsy …

Uncarboxylated osteocalcin induces antitumor immunity against mouse melanoma cell growth

Y Hayashi, T Kawakubo-Yasukochi… - Journal of …, 2017 - pmc.ncbi.nlm.nih.gov
Because of the poor response to chemotherapy and radiation therapy, new treatment
approaches by immune-based therapy involving activated T cells are required for …

Other targeted drugs in melanoma

M González-Cao, J Rodón… - Annals of …, 2015 - pmc.ncbi.nlm.nih.gov
Targeted therapy drugs are developed against specific molecular alterations on cancer
cells. Because they are “targeted” to the tumor, these therapies are more effective and better …

[HTML][HTML] Spinal nerve root extradural melanocytoma progressing to malignant melanoma: a case report with review of literature

S Shaikh, G Gupta, C Mohanty… - Asian Journal of …, 2021 - thieme-connect.com
Melanocytomas are rare benign pigmented tumors arising from the leptomeninges with a
very remote chance of progressing to malignant melanoma. They have a predilection for …