Interactions between bacterial and phage communities in natural environments

A Chevallereau, BJ Pons, S van Houte… - Nature Reviews …, 2022 - nature.com
We commonly acknowledge that bacterial viruses (phages) shape the composition and
evolution of bacterial communities in nature and therefore have important roles in ecosystem …

Horizontal gene transfer of antibiotic resistance genes in biofilms

C Michaelis, E Grohmann - Antibiotics, 2023 - mdpi.com
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …

[HTML][HTML] Massive expansion of human gut bacteriophage diversity

LF Camarillo-Guerrero, A Almeida, G Rangel-Pineros… - Cell, 2021 - cell.com
Bacteriophages drive evolutionary change in bacterial communities by creating gene flow
networks that fuel ecological adaptions. However, the extent of viral diversity and its …

Beyond horizontal gene transfer: the role of plasmids in bacterial evolution

J Rodríguez-Beltrán, J DelaFuente… - Nature Reviews …, 2021 - nature.com
Plasmids have a key role in bacterial ecology and evolution because they mobilize
accessory genes by horizontal gene transfer. However, recent studies have revealed that …

Systematic evaluation of horizontal gene transfer between eukaryotes and viruses

NAT Irwin, AA Pittis, TA Richards, PJ Keeling - Nature microbiology, 2022 - nature.com
Gene exchange between viruses and their hosts acts as a key facilitator of horizontal gene
transfer and is hypothesized to be a major driver of evolutionary change. Our understanding …

Antibiotic resistance genes in bacteria: Occurrence, spread, and control

Z Jian, L Zeng, T Xu, S Sun, S Yan… - Journal of basic …, 2021 - Wiley Online Library
The production and use of antibiotics are becoming increasingly common worldwide, and
the problem of antibiotic resistance is increasing alarmingly. Drug‐resistant infections …

Mutualistic interplay between bacteriophages and bacteria in the human gut

AN Shkoporov, CJ Turkington, C Hill - Nature Reviews Microbiology, 2022 - nature.com
Bacteriophages (phages) are often described as obligate predators of their bacterial hosts,
and phage predation is one of the leading forces controlling the density and distribution of …

Horizontal transfer of antibiotic resistance genes in the human gut microbiome

RS McInnes, GE McCallum, LE Lamberte… - Current opinion in …, 2020 - Elsevier
Highlights•The human gut microbiome harbours antibiotic resistance genes ('the
resistome').•Antibiotic resistance genes can spread in the gut microbiome through horizontal …

Bacteriophages benefit from mobilizing pathogenicity islands encoding immune systems against competitors

A Fillol-Salom, JT Rostøl, AD Ojiogu, J Chen, G Douce… - Cell, 2022 - cell.com
Bacteria encode sophisticated anti-phage systems that are diverse and versatile and display
high genetic mobility. How this variability and mobility occurs remains largely unknown …

The evolution of antibiotic resistance

RC MacLean, A San Millan - Science, 2019 - science.org
For most of human history, bacterial pathogens have been a major cause of disease and
mortality. The development of antibiotics provided a simple and effective treatment for …