SARS-CoV-2, COVID-19 and the aging immune system

JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …

Human monocyte subsets and phenotypes in major chronic inflammatory diseases

TS Kapellos, L Bonaguro, I Gemünd, N Reusch… - Frontiers in …, 2019 - frontiersin.org
Human monocytes are divided in three major populations; classical (CD14+ CD16−), non-
classical (CD14dimCD16+), and intermediate (CD14+ CD16+). Each of these subsets is …

M1/M2 macrophages and their overlaps–myth or reality?

Z Strizova, I Benesova, R Bartolini… - Clinical …, 2023 - portlandpress.com
Macrophages represent heterogeneous cell population with important roles in defence
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …

The role of macrophages in acute and chronic wound healing and interventions to promote pro-wound healing phenotypes

P Krzyszczyk, R Schloss, A Palmer… - Frontiers in …, 2018 - frontiersin.org
Macrophages play key roles in all phases of adult wound healing, which are inflammation,
proliferation, and remodeling. As wounds heal, the local macrophage population transitions …

Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity

L Vanderbeke, P Van Mol, Y Van Herck… - Nature …, 2021 - nature.com
Epidemiological and clinical reports indicate that SARS-CoV-2 virulence hinges upon the
triggering of an aberrant host immune response, more so than on direct virus-induced …

Skin acute wound healing: a comprehensive review

L Cañedo-Dorantes… - International journal of …, 2019 - Wiley Online Library
Experimental work of the last two decades has revealed the general steps of the wound
healing process. This complex network has been organized in three sequential and …

Monocytes and macrophages in COVID-19: Friends and foes

S Meidaninikjeh, N Sabouni, HZ Marzouni, S Bengar… - Life sciences, 2021 - Elsevier
The COVID-19 is a novel infectious disease caused by SARS-CoV-2 and is known as a
pandemic emergency that has led to a high rate of mortality throughout the world. Evidence …

Monocytes in rheumatoid arthritis: Circulating precursors of macrophages and osteoclasts and, their heterogeneity and plasticity role in RA pathogenesis

AK Rana, Y Li, Q Dang, F Yang - International immunopharmacology, 2018 - Elsevier
Rheumatoid arthritis (RA) is a chronic systemic, autoimmune and inflammatory disease
represented as synovitis, pannus formation, adjacent bone erosions, and joint destruction …

Non-coding RNAs regulation of macrophage polarization in cancer

S Mohapatra, C Pioppini, B Ozpolat, GA Calin - Molecular cancer, 2021 - Springer
Noncoding RNA (ncRNA) transcripts that did not code proteins but regulate their functions
were extensively studied for the last two decades and the plethora of discoveries have …

Monocyte subsets: phenotypes and function in tuberculosis infection

P Sampath, K Moideen, UD Ranganathan… - Frontiers in …, 2018 - frontiersin.org
Monocytes are critical defense components that play an important role in the primary innate
immune response. The heterogeneous nature of monocytes and their ability to differentiate …