Aliphatic polycarbonates have gained increased attention as biomaterials largely owing to
their biocompatibility and tunable degradation. Moreover, the ability to introduce functional …

Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

Plasma membrane rupture is a promising strategy for drug-resistant cancer treatment, but its
application is limited by the low tumour selectivity of membranolytic molecules. Here we …

Nanomedicines have the potential to provide advanced therapeutic strategies in combating
tumors. Polymer‐prodrug‐based nanomedicines are particularly attractive in cancer …

Nanoparticle-based targeting of overexpressed cell-surface receptors is a promising
strategy that provides precise delivery of drugs to cancer cells. In the present study, we …

Cancer is increasingly becoming a serious threat to human life and health. Therefore, the
development of safe and effective therapeutic agents against the disease is of crucial …

Cationic polymers have great potential for cancer therapy due to their unique interactions
with cancer cells. However, their clinical application remains limited by their high toxicity …

Engineered nanomaterials have been extensively employed as therapeutics for tumor
management. Meanwhile, the complex tumor niche along with multiple barriers at the …

Drug-free macromolecular therapeutics are promising alternatives to traditional drugs.
Nanomedicines with multiple organelles targeting can potentially increase the efficacy …

Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …