Gut microbiota determines the fate of dietary fiber-targeted interventions in host health

W Wang, Z Fan, Q Yan, T Pan, J Luo, Y Wei, B Li… - Gut …, 2024 - Taylor & Francis
Epidemiological investigation confirmed that the intake of dietary fiber (DF) is closely related
to human health, and the most important factor affecting the physiological function of DF …

Exploiting gut microbial traits and trade-offs in microbiome-based therapeutics

B Liu, DR Garza, P Saha, X Zhou, K Faust - Nature Reviews …, 2024 - nature.com
The clinical translation of therapeutics on the basis of human gut microorganisms is
hampered by our limited knowledge of how microbes survive and adapt to fluctuating …

Mucin-driven ecological interactions in an in vitro synthetic community of human gut microbes

MD Berkhout, A Ioannou, C de Ram, S Boeren… - …, 2024 - academic.oup.com
Specific human gut microbes inhabit the outer mucus layer of the gastrointestinal tract.
Certain residents of this niche can degrade the large and complex mucin glycoproteins that …

MetaBiome: A Multiscale Model Integrating Agent-Based Modeling and Metabolic Networks Reveals Spatial Regulation in Mucosal Microbial Communities

J Aminian-Dehkordi, AM Dickson, A Valiei, M Mofrad - bioRxiv, 2024 - biorxiv.org
Mucosal microbial communities (MMCs) are complex ecosystems near the mucosal layers of
the gut, essential for maintaining health and modulating disease states. Despite advances in …

Identification of strain-specific cues that regulate biofilm formation in Bacteroides thetaiotaomicron

RWP Glowacki, MJ Engelhart, JM Till, A Kadam… - bioRxiv, 2024 - biorxiv.org
Members of the gut microbiome encounter a barrage of host-and microbe-derived
microbiocidal factors that must be overcome to maintain fitness in the intestine. The long …

Discovery of alternative stable states in a synthetic human gut microbial community

DR Garza, B Liu, C van de Velde, P Saha, X Zhou… - bioRxiv, 2024 - biorxiv.org
Several human-associated microbial communities exist in multiple configurations and can
change their composition in response to perturbations, remaining in an altered state even …

Discovery of alternative stable states in a synthetic human gut microbial community

K Faust, D Garza, B Liu, C van de Velde, P Saha… - 2025 - researchsquare.com
Several human-associated microbial communities exist in multiple configurations and can
change their composition in response to perturbations, remaining in an altered state even …

The Role of the Gut Microbiome in Modulating Arterial Dysfunction With Aging

NT Greenberg - 2024 - search.proquest.com
Advancing age is the primary non-modifiable risk factor influencing the development of
cardiovascular diseases (CVDs), the leading cause of death in developed nations. Age …

Gut Microbiome-Targeted Interventions for Improving Age-Related Arterial Dysfunction

AG Longtine - 2023 - search.proquest.com
Advancing age leads to declines in physiological function and greatly increases risk for the
development of numerous diseases, including cardiovascular (CV), neurodegenerative, and …