[HTML][HTML] Clinical practice updates in the management of immune thrombocytopenia

AM Khan, H Mydra, A Nevarez - Pharmacy and Therapeutics, 2017 - ncbi.nlm.nih.gov
Immune thrombocytopenia (ITP), previously called idiopathic thrombocytopenia purpura, is
an autoimmune disorder characterized by a severe reduction in peripheral blood platelet …

On the maturation of megakaryocytes: a review with original observations on human in vivo cells emphasizing morphology and ultrastructure

YX Ru, SX Zhao, SX Dong, YQ Yang… - Ultrastructural …, 2015 - Taylor & Francis
Megakaryocytes engage in the synthesis of a variety of molecular and macromolecular
constituents to build-up characteristic megakaryocyte structure and form proplatelets in a …

[HTML][HTML] Changes in follicular helper T cells in idiopathic thrombocytopenic purpura patients

J **e, D Cui, Y Liu, J **, H Tong, L Wang… - … journal of biological …, 2015 - ncbi.nlm.nih.gov
Background: Idiopathic thrombocytopenic purpura (ITP) is a primary autoimmune disease
with a decreased platelet count caused by platelet destruction mediated mainly by platelet …

[PDF][PDF] Immune thrombocytopenia: pathogenesis and treatment approaches

AB Raj - J Hematol Transfus, 2017 - academia.edu
Immune thrombocytopenia (ITP) is a common hematologic disorder affecting both adult and
pediatric patients. Pathogenesis of ITP involves 2 major mechanisms: increased platelet …

Eltrombopag therapy in newly diagnosed steroid non-responsive ITP patients

AK Tripathi, A Shukla, S Mishra, YS Yadav… - International journal of …, 2014 - Springer
Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterised by
isolated thrombocytopenia (peripheral blood platelet count< 100× 10 9/L) in the absence of …

Temporal trends and outcome of splenectomy in adults with immune thrombocytopenia in the USA

A Finianos, H Mujadzic, H Peluso, T Mujadzic… - Annals of …, 2021 - Springer
Splenectomy is one of the treatments of immune thrombocytopenia (ITP) with a high
response rate. However, it is an irreversible procedure that can be associated with morbidity …

[HTML][HTML] Retrospective Evaluation of Survival and Prognostic Factors in Immune Thrombocytopenia: A Single-Center and Cross-Sectional Study

G Pektaş, İA Uncu, Y Dere, Ş Öncü, MB Kızılkaya… - Medicina, 2024 - mdpi.com
Background and Objectives: Immune thrombocytopenia (ITP) is an autoimmune disease
characterized by the autoantibody-mediated destruction of platelets. The treatment of ITP …

A megakaryocyte morphological classification-based predictive model for steroid sensitivity in primary immune thrombocytopenia

J Zhu, R Chen, S Zhao, L Zhu, X Li, M **e, X Ye - Platelets, 2020 - Taylor & Francis
The first-line therapy for primary immune thrombocytopenia (ITP) is steroids, but about one-
third of patients do not respond to steroids. Recent studies have shown megakaryocyte (MK) …

Evaluation of the hematological inflammatory parameters in the patients with immune thrombocytopenic purpura: A case–control study

MH Ahmadi, M Maleknia, R Khoshbakht… - Health Science …, 2024 - Wiley Online Library
Abstract Background and Aims Inflammation is one of the immune thrombocytopenic
purpura (ITP)'s aggravating elements due to inflammatory cells' function. This study aims to …

Association between megakaryocyte abnormalities on bone marrow smear and response to thrombopoietin receptor agonists in adult patients with primary immune …

O Walter, A Ribes, J Germain, JB Rieu, T Comont… - Platelets, 2022 - Taylor & Francis
Impaired platelet production is a mechanism of immune thrombocytopenia (ITP).
Morphological abnormalities of megakaryocytes (MKs) are sometimes observed in this …