Intervertebral disc degeneration (IVDD), a widely recognized cause of lower back pain, is
the leading cause of disability worldwide. A myriad of preclinical in vivo animal models of …

The intervertebral disc (IVD) is the fibrocartilaginous joint located between each vertebral
body that confers flexibility and weight bearing capabilities to the spine. The IVD plays an …

Study Design. Measurement and normalization of disc geometry parameters for several
animal models used in disc research. Objectives. To compare normalized values of disc …

Study Design. Experimental measurement and normalization of in vitro disc axial
compression mechanics and glycosaminoglycan and water content for several animal …

Intervertebral disc (IVD) degeneration is a challenging clinical problem that urgently
demands viable nucleus pulposus (NP) implant materials. The best suited biomaterial for NP …

Study Design. Microstructural investigation of compression-induced disruption of the flexed
lumbar disc. Objective. To provide a microstructural analysis of the mechanisms of annular …

Study Design. The contents of DNA, proteoglycan, type II collagen, and denatured type II
collagen in the bovine coccygeal intervertebral discs were examined in situ in relation to …

In this study, the stability and biocompatibility of methacrylated gellan gum hydrogels,
obtained either by ionic‐(iGG‐MA) or photo‐crosslinking (phGG‐MA), were evaluated in …

An important part of designing successful products is building empathy for the people for
whom the product is intended. Despite recent interest in empathic design techniques, they …

Objective. To perform lateral approach lumbar surgery in an ovine model to administer an
injectable riboflavin cross-linked high-density collagen (HDC) gel and to assess its ability to …