Endothelium-derived relaxing factors (EDRFs), including nitric oxide (NO), prostacyclin (PGI
2), and endothelium-derived hyperpolarizing factor (EDHF), play pivotal roles in regulating …

First published in 1990: The Endothelium: Modulator of Cardiovascular Function takes a
comprehensive look at the role of the endothelium in cardiovascular control in health and …

The endothelium modulates the tone of the underlying vascular smooth muscle by releasing
relaxing factors, including prostacyclin, nitric oxide (NO), and endothelium-derived …

This study investigated the effects of exercise training on the regional release of
endothelium-derived nitric oxide (EDNO) in spontaneously hypertensive rats (SHR). Male …

Endothelium-dependent relaxations are depressed in hypertension. In this study we
investigated the possible involvement of endothelium-dependent smooth muscle …

In previous studies in stroke-prone spontaneously hypertensive rats (SHRSP), we
demonstrated that early-onset, long-term angiotensin-converting enzyme inhibitor treatment …

Background: The aim of this study was to assess the effects of N-acetylcysteine (NAC) on
nitric oxide and adrenergic pathways in mesenteric artery from spontaneously hypertensive …

To determine the mechanism (s) involved in vasorelaxation of small arteries from
hypertensive rats, normotensive (NORM), angiotensin II-infused (ANG), high-salt (HS), ANG …

As a source of several vasoactive factors, the endothelium takes part in the regulation of
vascular tone. The most important endothelium‐derived vasoactive substances are nitric …

Although Danhong injection (DHI) is one of the most prescribed cardiovascular medicines in
China, its therapeutic indications and mechanisms remain partially defined. We now identify …